Detailed information of TA system TA178950

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC(toxin)
• Location: 1886447..1887099
• Replicon: chromosome
• Accession: NZ_CP063845
• Organism: Gloeobacter morelensis MG652769

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: ISF26_RS09185
• Protein ID: WP_230843597.1
• Coordinates: 1886447..1886824 (-)
• Length: 126 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: ISF26_RS09190
• Protein ID: WP_230843598.1
• Coordinates: 1886821..1887099 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ISF26_RS09155 (ISF26_09095)	1881650..1881934	+	285	WP_230843591.1	type II toxin-antitoxin system ParD family antitoxin	-
ISF26_RS09160 (ISF26_09100)	1881934..1882236	+	303	WP_230843592.1	type II toxin-antitoxin system RelE/ParE family toxin	-
ISF26_RS09165 (ISF26_09105)	1882400..1882615	+	216	WP_230843593.1	hypothetical protein	-
ISF26_RS09170 (ISF26_09110)	1882762..1884312	-	1551	WP_230843594.1	family 1 glycosylhydrolase	-
ISF26_RS09175 (ISF26_09115)	1884315..1885445	-	1131	WP_230843595.1	UDP-N-acetylglucosamine--LPS N-acetylglucosamine transferase	-
ISF26_RS09180 (ISF26_09120)	1885526..1885723	-	198	WP_230843596.1	hypothetical protein	-
ISF26_RS09185 (ISF26_09125)	1886447..1886824	-	378	WP_230843597.1	type II toxin-antitoxin system VapC family toxin	Toxin
ISF26_RS09190 (ISF26_09130)	1886821..1887099	-	279	WP_230843598.1	type II toxin-antitoxin system VapB family antitoxin	Antitoxin
ISF26_RS09195 (ISF26_09135)	1887332..1887583	+	252	WP_230843599.1	hypothetical protein	-
ISF26_RS09200 (ISF26_09140)	1887577..1888464	-	888	WP_230843600.1	GNAT family N-acetyltransferase	-
ISF26_RS09205 (ISF26_09145)	1888858..1889682	+	825	WP_230843601.1	phycobilisome rod-core linker polypeptide	-
ISF26_RS09210 (ISF26_09150)	1889809..1890297	-	489	WP_230841971.1	phycocyanin subunit alpha	-
ISF26_RS09215 (ISF26_09155)	1890330..1890848	-	519	WP_230841972.1	phycocyanin subunit beta	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-118)

Antitoxin

• Antitoxin VapB-like (4-85)

Sequences

Toxin

Protein

• Length: 126 a.a.
• Molecular weight: 13404.45 Da
• Isoelectric Point: 4.4002

>T178950 WP_230843597.1 NZ_CP063845:c1886824-1886447 [Gloeobacter morelensis MG652769]
MIAIDTSAIVAILLGEPEAERFARAIEQDEEPLLSAASLVELFLVMKHKQGSASAPLIEQFLATGGISVCSVTPEQARRA
QEAAYRFGILNFGDVFSYALAKERGIGLLFKGTDFAVTDLIAAPF

Nucleotide

• Length: 378 bp

>T178950 NZ_CP084433:1711626-1711904 [Edwardsiella piscicida]
ATGATCAAAAGCTTCAAGCATCAGGGGTTGAAAAAATTCTTCCTCAACAATGATAGTGGCGGACTTGAGCAACACGTGGT
GCCACGGATCAGGACACGGCTGACCACCATTGATGCGGCAGACTGCATCGACGGTATCAACATGCCCGGCTACGATTTGC
ATCCACTGAAAGGCGATCGCAAAGATATTTGGTCGATAAAAGTGTCTGGCAATTGGCGTATCACTTTCCGCTTTATCGAT
GGTGATGCGGAGATCCTGAATCTGGAGGACTATCACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10329.85 Da
• Isoelectric Point: 9.7734

>AT178950 WP_230843598.1 NZ_CP063845:c1887099-1886821 [Gloeobacter morelensis MG652769]
MQQINIKSDKAYRMANELSRLTGESVTQAITQAIEERLEKIRAQARSRREGIAERLLALGTRSVALPILDPRAPDEILYD
ENGLPKNPMAAR

Nucleotide

• Length: 279 bp

>AT178950 NZ_CP084433:1711904-1712191 [Edwardsiella piscicida]
ATGAAAATGGCTAACCCTGCGCATCCCGGCGAAATCATCGCTGAGACACTGGAGGATATGCATATCAGCCTGCGGCAGTT
CGCCAAGGCGATGGATATTGCGCCCTCCACCGCCAGCCGGCTGATCTCTGGCCACACCTCGGTTACCCCGGAAATGGCGC
TGCGCCTGTCTGTGGTGCTCGGCAGTACGGCAGAAACCTGGCTCAAGATCCAGAACCACTACAGCCTGAACGAGGCCAGA
AAAACCACTGACCTGTGCCACCTGCACCGCTTGGTAGTGGCCTCCTGA