Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii(toxin)
Location 568665..570101 Replicon chromosome
Accession NZ_CP063845
Organism Gloeobacter morelensis MG652769

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag ISF26_RS02755 Protein ID WP_230842395.1
Coordinates 568665..569576 (-) Length 304 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag ISF26_RS02760 Protein ID WP_230842397.1
Coordinates 569586..570101 (-) Length 172 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISF26_RS02735 (ISF26_02725) 563851..565194 + 1344 WP_230842391.1 IS701 family transposase -
ISF26_RS02740 (ISF26_02730) 565534..566721 - 1188 WP_230842392.1 threonine synthase -
ISF26_RS02745 (ISF26_02735) 566826..567236 + 411 WP_230842393.1 CAP domain-containing protein -
ISF26_RS02750 (ISF26_02740) 567398..568597 - 1200 WP_230842394.1 BREX system Lon protease-like protein BrxL -
ISF26_RS02755 (ISF26_02745) 568665..569576 - 912 WP_230842395.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
ISF26_RS02760 (ISF26_02750) 569586..570101 - 516 WP_230842397.1 transcriptional regulator Antitoxin
ISF26_RS02765 (ISF26_02755) 570311..570808 - 498 WP_230842399.1 hypothetical protein -
ISF26_RS02770 (ISF26_02760) 570805..571839 - 1035 WP_230842400.1 hypothetical protein -
ISF26_RS02775 (ISF26_02765) 572313..572468 - 156 WP_230842402.1 hypothetical protein -
ISF26_RS02780 (ISF26_02770) 572634..573224 + 591 WP_230842404.1 CAP domain-containing protein -
ISF26_RS02785 (ISF26_02775) 573233..573679 - 447 WP_230842405.1 hypothetical protein -
ISF26_RS02790 (ISF26_02780) 573798..574094 + 297 WP_230842407.1 DUF2470 domain-containing protein -
ISF26_RS02795 (ISF26_02785) 574106..574486 + 381 WP_230842408.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-264)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 304 a.a.        Molecular weight: 34776.02 Da        Isoelectric Point: 5.3202

>T178947 WP_230842395.1 NZ_CP063845:c569576-568665 [Gloeobacter morelensis MG652769]
MPKPVRNIAASVRQRLLEKSKKTGENFQFVVERYALERALYRLSKSKYAELFILKGGMLISLWTDQPYRSTRDVDVLVFG
QSDPEYLVSVFNEICSLDVEKDGLMFLVKDIRNEPIKEEQQYGGTRLNFGAKLGDIRVTVQFDISFGDAVTPTAEWREYP
CILPESPTPRLRIYPIETVVAEKFETMVNLANSRMKDYYDIFFLQKLFEFNGAILAEAIRNTFDRRGREIPEELPEGLTA
TFFADPSKIQQWNALVRKNPSQMPQLALEEVVGALQQFLMPPARAAAQMQELQAIWTPGKGWT

Download         Length: 912 bp

>T178947 NZ_CP084432:c3100785-3100444 [Edwardsiella tarda]
ATGAAAACTCTACCTGCTACAATTTCGCGGGCTGCGAAGCCATGTCTGTCGCCAGTGGCTGTCTGGCAAATGTTACTGAC
ACGCCTGCTTGAACAACACTATGGCCTGACACTGAACGACACGCCATTTAGTGATGAAACTGTGATTCAGGAACACATTG
ATGCCGGTATCACGCTGGCTGATGCCGTTAACTTTCTGGTGGATAAGTACGAGCTGGTTCGTATCGATCGCAGAGGGTTT
AGTTGGCAAGAACAATCACCTTATCTTCGGGCCGTTGATATTCTGCGAGCACGACAGGCAACTGGCTTGTTGCGACGGAG
CCGTAATAACGCTGTATCGTGA

Antitoxin


Download         Length: 172 a.a.        Molecular weight: 19281.50 Da        Isoelectric Point: 9.3647

>AT178947 WP_230842397.1 NZ_CP063845:c570101-569586 [Gloeobacter morelensis MG652769]
MRALERQGLVEQVSPGVWRDLRVEPSIHHSLVEPAFRAPQGVVCLLSALQFHGLTTQQPSVVWFAIANKAQPPKTVETRL
RPIRMSEASLSAGVEIHQIEAIPVRIFCPAKTVADCFKFRNQVGLDVALEALRDCYRRRRASVADLLHYARICRVARVMQ
PYLETIIELSS

Download         Length: 516 bp

>AT178947 NZ_CP084432:c3101126-3100806 [Edwardsiella tarda]
ATGAGAAGTCATGTCACATGGGGGCTGCAGCGGGATATTACGCCACACCTGGGAACCCGTCTGGTGCAGGAGGGCAACCG
GCTGCATTATCTGGCTGACCGGGCCAGCATCACTGGTAAATTCAGTGACGCCGAATTCCGGAAGCTGGATGAAACATTCC
CGCACTTTATCAGCCAGATGGAGTCGATGCTGACCACCGATGAACTGAATCCCCGTCATGCCCACTGCGTCACCCTGTAC
CACAACGGTTTTACCTGCGAAGCCGATACTCTTGGTAGTTGCGGCTACGTATATATCGCTGTTTATCCCACTCAACGCTA
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References