Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1098324..1098846 Replicon chromosome
Accession NZ_CP063839
Organism Sphingopyxis granuli strain RW412

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ICN83_RS05075 Protein ID WP_067186158.1
Coordinates 1098324..1098611 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ICN83_RS05080 Protein ID WP_067112971.1
Coordinates 1098598..1098846 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ICN83_RS05055 (ICN83_05055) 1094320..1095195 - 876 WP_212598362.1 F0F1 ATP synthase subunit gamma -
ICN83_RS05060 (ICN83_05060) 1095272..1096801 - 1530 WP_212598363.1 F0F1 ATP synthase subunit alpha -
ICN83_RS05065 (ICN83_05065) 1096805..1097371 - 567 WP_212598364.1 F0F1 ATP synthase subunit delta -
ICN83_RS05070 (ICN83_05070) 1097638..1098327 + 690 WP_212598365.1 dienelactone hydrolase family protein -
ICN83_RS05075 (ICN83_05075) 1098324..1098611 - 288 WP_067186158.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ICN83_RS05080 (ICN83_05080) 1098598..1098846 - 249 WP_067112971.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
ICN83_RS05085 (ICN83_05085) 1098878..1100413 - 1536 WP_212598366.1 serine protease -
ICN83_RS05090 (ICN83_05090) 1100600..1100698 + 99 Protein_1012 DUF1203 domain-containing protein -
ICN83_RS05095 (ICN83_05095) 1100695..1101729 + 1035 WP_067112978.1 bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada -
ICN83_RS05100 (ICN83_05100) 1101726..1102496 + 771 WP_212598367.1 isocitrate lyase/phosphoenolpyruvate mutase family protein -
ICN83_RS05105 (ICN83_05105) 1103068..1103526 + 459 WP_148650925.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(11-74)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11208.97 Da        Isoelectric Point: 10.4983

>T178938 WP_067186158.1 NZ_CP063839:c1098611-1098324 [Sphingopyxis granuli]
MTTYNLDFFKDAKKEWDRLDKSVRAQFRKKLTQRLANPHIPSARLSGMANCYKIKLRSAGYRLIYQVEDETITVVVVAIG
KRERNEAYEEAKRRL

Download         Length: 288 bp

>T178938 NZ_CP084430:1676971-1677249 [Edwardsiella piscicida]
ATGATCAAAAGCTTCAAGCATCAGGGGTTGAAAAAATGCTTCCTCAACAATGATAGTGGCGGACTTGAGCAACACGTGGT
GCCACGGATCAGGACACGGCTGACCACCATTGATGCGGCAGACTGCATCGACGGTATCAACATGCCCGGCTACGATTTGC
ATCCACTGAAAGGCGATCGCAAAGATATCTGGTCGATAAAAGTGTCTGGCAATTGGCGTATCACTTTCCGCTTTATCGAT
GGTGATGCGGAGATCCTGAATCTGGAGGACTATCACTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8938.22 Da        Isoelectric Point: 4.4091

>AT178938 WP_067112971.1 NZ_CP063839:c1098846-1098598 [Sphingopyxis granuli]
MGKPLLADFGISISELKKNPSAAIRAADGAPVAILNRNTPEAYLVPADAWEAILDALDDIELARIVRERQGQERIRVSID
DL

Download         Length: 249 bp

>AT178938 NZ_CP084430:1677249-1677536 [Edwardsiella piscicida]
ATGAAAATGGCTAACCCTGCGCATCCCGGCGAAATCATCGCTGAGACACTGGAGGATATGCATATCAGCCTGCGGCAGTT
CGCCAAGGCGATGGATATTGCGCCCTCCACCGCCAACCGGCTGATCTCTGGCCACACCTCGGTCACCCCGGAAATGGCGC
TGCGCCTGTCTGTGGTGCTCGGCAGTACGGCAGAAACCTGGCTCAAGATCCAGAACCACTACAGCCTGAACGAGGCCAGA
AAAACCACTGACCTGTGCCACCTGCACCGCTTGGTAGTGGCCTCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References