Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2018345..2018490 Replicon chromosome
Accession NZ_CP063833
Organism Klebsiella pneumoniae strain CRKP66R

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2018381..2018483 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2018345..2018490 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IRT47_RS09880 2013475..2015535 + 2061 WP_004151449.1 oligopeptidase B -
IRT47_RS09885 2015539..2016198 - 660 WP_002911407.1 exodeoxyribonuclease X -
IRT47_RS09890 2016277..2016507 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IRT47_RS09895 2016620..2016994 + 375 WP_004151448.1 CopC domain-containing protein YobA -
IRT47_RS09900 2016998..2017867 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
IRT47_RS09905 2017884..2018222 + 339 WP_002911404.1 YebY family protein -
- 2018345..2018490 - 146 - - Antitoxin
- 2018381..2018483 + 103 - - Toxin
IRT47_RS09910 2018858..2019001 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
IRT47_RS09915 2019106..2020074 - 969 WP_004151446.1 VirK/YbjX family protein -
IRT47_RS09920 2020231..2020884 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
IRT47_RS09925 2020881..2021072 - 192 WP_002911395.1 YebW family protein -
IRT47_RS09930 2021170..2021409 - 240 WP_002911393.1 YebV family protein -
IRT47_RS09935 2021525..2022958 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T178911 NZ_CP063833:2018381-2018483 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT178911 NZ_CP063833:c2018490-2018345 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References