Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-YefM
Location 1434389..1434897 Replicon chromosome
Accession NZ_CP063814
Organism Microbacterium sp. A18JL200

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag IM777_RS06990 Protein ID WP_194385054.1
Coordinates 1434637..1434897 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag IM777_RS06985 Protein ID WP_194385053.1
Coordinates 1434389..1434640 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IM777_RS06960 1430529..1430819 - 291 Protein_1361 transposase -
IM777_RS06965 1430827..1432224 - 1398 WP_071044142.1 IS30 family transposase -
IM777_RS06970 1432870..1433178 - 309 WP_071044140.1 transposase -
IM777_RS06975 1433225..1433749 - 525 WP_194385051.1 hypothetical protein -
IM777_RS06980 1433877..1434116 - 240 WP_194385052.1 hypothetical protein -
IM777_RS06985 1434389..1434640 + 252 WP_194385053.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IM777_RS06990 1434637..1434897 + 261 WP_194385054.1 Txe/YoeB family addiction module toxin Toxin
IM777_RS06995 1435037..1435498 + 462 WP_194385055.1 GNAT family N-acetyltransferase -
IM777_RS07000 1435697..1436656 + 960 WP_194385056.1 aldo/keto reductase -
IM777_RS07005 1436678..1438573 - 1896 WP_194385057.1 cadmium-translocating P-type ATPase -
IM777_RS07010 1438570..1438965 - 396 WP_194385058.1 metalloregulator ArsR/SmtB family transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10225.57 Da        Isoelectric Point: 7.3146

>T178899 WP_194385054.1 NZ_CP063814:1434637-1434897 [Microbacterium sp. A18JL200]
VTRSLAFDPNGWEDYVYWQTQDRKTLKRINLLIADVVRDPFDGIGKPEPLRHVLSGAWSRRIDEKNRLVYYVTDDHIVIL
QARDHY

Download         Length: 261 bp

>T178899 NZ_CP084406:529578-529985 [Sphingobium sp. CFD-2]
ATGATCGTTCTCGACACCAATGTCGTTTCCGAGGCGATGAAACCGGAACCGGCTCCCGCCGTGCGCGACTGGCTCGACGA
GCAGGCCGCCGAGACCCTCTATCTCTCCAGCATCACCGTCGCCGAACTGTTGTTCGGCATCGCAGTCCTGCCGGACGGAC
GGCGCAAGCAAAAGCTCGCGGCCACGCTCGACGGGATGCTCGACCTGTTCGACGGCAGAATCCTTCCCTTCGATACTTCT
GCCGCCCGTCATTATGCCGACCTTGCCGTGAGCGCCCGCAAAGCTGGCAAGGGCTTTCCGACACCGAATGGCTACATCGC
GGCCATCGCCACCGTTCACGGATTTGCGGTCGCCACACGAGACGATAGCGCCTTCGTTGCCGCTGGAGTCGCAGTGATCC
ACCCTTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9315.42 Da        Isoelectric Point: 4.8047

>AT178899 WP_194385053.1 NZ_CP063814:1434389-1434640 [Microbacterium sp. A18JL200]
MSAITATEARKSLFGLIQQVNEDHTTVEVVSRRGNAVIMSKDDFDALTETAYLLRNPANAERLLEAVERARRGEFQQHDL
LDA

Download         Length: 252 bp

>AT178899 NZ_CP084406:529327-529581 [Sphingobium sp. CFD-2]
ATGCCCGCCGTCACCATTCGCAACTTGTCCGACGAGACACACCGCGCCCTCAAGGTGCGCGCCGCCCATCATGGGCGCAG
CGCCGAAGCCGAAATGCGCGACATTCTTGAAGCGGCGGTTCGTCCCGCGAACCGTCTTCGCATCGGCTCGGCCCTCTCGG
CCTTGAGCCGCGATGCCGGGCTGACCAATGCCGATTTCGAGGCGCTGGAACAGGGCCGCGATCGGACGCCTGCCAAGCCC
ATGAGCTTTAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References