Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 145980..146536 Replicon chromosome
Accession NZ_CP063813
Organism Microbacterium sp. WY121

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IR212_RS00695 Protein ID WP_194397138.1
Coordinates 145980..146255 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IR212_RS00700 Protein ID WP_194397139.1
Coordinates 146252..146536 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IR212_RS00675 142280..143044 + 765 WP_194397135.1 hypothetical protein -
IR212_RS00680 143211..143813 + 603 WP_194397136.1 hypothetical protein -
IR212_RS00685 144038..144130 + 93 Protein_133 DUF2510 domain-containing protein -
IR212_RS00690 145319..145927 + 609 WP_194397137.1 recombinase family protein -
IR212_RS00695 145980..146255 - 276 WP_194397138.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IR212_RS00700 146252..146536 - 285 WP_194397139.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IR212_RS00705 147056..147253 + 198 WP_194397140.1 hypothetical protein -
IR212_RS00710 147338..147775 + 438 WP_194397141.1 VOC family protein -
IR212_RS00715 147809..148582 - 774 WP_194398444.1 tryptophan-rich sensory protein -
IR212_RS00720 148748..150088 - 1341 WP_194397142.1 class I SAM-dependent methyltransferase -
IR212_RS00725 150085..151464 - 1380 WP_194397143.1 FAD-binding oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(34-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10436.02 Da        Isoelectric Point: 9.4963

>T178898 WP_194397138.1 NZ_CP063813:c146255-145980 [Microbacterium sp. WY121]
VIGPYEVVFTRSARRALEVTLPESVAAAVFEFIVGPLAANPTRLGNPLREPLAPLYSARRGEYRVLYRIEDDRLVIEIVT
IEHRRDAYQRR

Download         Length: 276 bp

>T178898 NZ_CP084405:3534430-3534717 [Sphingobium sp. CFD-2]
ATGGCCATCAAACTCACCCGCTTTGACGCGGCGGAATATCTGACCGAACCGGAGGATCAGGCCGAACTGCTGGCAGACGC
CCTCACAACCGGCGATGTCCATGTCATCGCAAAAGCCATCGGTATCGTGGCCCGCGCTCATGGCATGACGGAACTGTCGA
AGGAGACCGGCATCAAGCGTCAGCAGCTTTACCGTGCCCTCGGCCCGGACGGAAACCCTACGCTGGAAACCATGCTCAAG
GTGCTGCCCGCGCTCGGCCTACGCATGCGAATCGAGGCTGCCGCTTAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10052.24 Da        Isoelectric Point: 4.3423

>AT178898 WP_194397139.1 NZ_CP063813:c146536-146252 [Microbacterium sp. WY121]
MTVLSLADARASLSKHIESAATTHERFEITRNGARVAVLLSAEDYDALVETVDILSRPDEVAALREAIAELESGDVSSAD
EVRAAMVARGRLAE

Download         Length: 285 bp

>AT178898 NZ_CP084405:3534107-3534397 [Sphingobium sp. CFD-2]
ATGGAAACGCAACAGACCCCGGCCTTCGCTGATTGGTTCGAAAGCCTTCGCGATCGCAAGGCGAAGTCGAAGATCGCGGG
CAGGATCGCCCGCATCGAACTCGGCCTGATGGGCGATGTGAAGTCGGTTGGCGACGGCGTTTCGGAGGCGCGTATCGACT
TCGGCCCCGGATACCGCCTCTATTTCACCCGCCGGGGCGAGCAGTTGATTATCCTGCTGGTGGGCGGCGACAAGTCAAGC
CAGCAGCGGGACATCGCAAAGGCAAAGGAAATGGCGGCTCAGATATCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References