Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 894768..895358 Replicon chromosome
Accession NZ_CP063780
Organism Pseudomonas sp. OST1909

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IH404_RS03855 Protein ID WP_005784367.1
Coordinates 895059..895358 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID I4KVR9
Locus tag IH404_RS03850 Protein ID WP_005784366.1
Coordinates 894768..895055 (-) Length 96 a.a.

Genomic Context

IH404_RS03870IH404_RS03875IH404_RS03830IH404_RS03835IH404_RS03840IH404_RS03845IH404_RS03850IH404_RS03855IH404_RS03860IH404_RS03865
Location: 897675..899021 (1347 bp)
Type: Others
Protein ID: WP_194439976.1
Location: 899014..899640 (627 bp)
Type: Others
Protein ID: WP_005784376.1
Location: 891196..893256 (2061 bp)
Type: Others
Protein ID: WP_005784358.1
Location: 893350..893739 (390 bp)
Type: Others
Protein ID: WP_032803236.1
Location: 893749..894231 (483 bp)
Type: Others
Protein ID: WP_005784362.1
Location: 894279..894671 (393 bp)
Type: Others
Protein ID: WP_005784364.1
Location: 894768..895055 (288 bp)
Type: Antitoxin
Protein ID: WP_005784366.1
Location: 895059..895358 (300 bp)
Type: Toxin
Protein ID: WP_005784367.1
Location: 895706..896434 (729 bp)
Type: Others
Protein ID: WP_005784369.1
Location: 896431..897636 (1206 bp)
Type: Others
Protein ID: WP_194439975.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
IH404_RS03830891196..893256-2061WP_005784358.1TonB-dependent copper receptor-
IH404_RS03835893350..893739-390WP_032803236.1DUF2946 domain-containing protein-
IH404_RS03840893749..894231-483WP_005784362.1copper chaperone PCu(A)C-
IH404_RS03845894279..894671-393WP_005784364.1DUF2946 domain-containing protein-
IH404_RS03850894768..895055-288WP_005784366.1putative addiction module antidote proteinAntitoxin
IH404_RS03855895059..895358-300WP_005784367.1type II toxin-antitoxin system RelE/ParE family toxinToxin
IH404_RS03860895706..896434-729WP_005784369.1cobalt-precorrin-6A reductase-
IH404_RS03865896431..897636-1206WP_194439975.1precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE-
IH404_RS03870897675..899021+1347WP_194439976.1precorrin-3B synthase-
IH404_RS03875899014..899640+627WP_005784376.1precorrin-8X methylmutase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-95)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11515.17 Da        Isoelectric Point: 10.2241

>T178829 WP_005784367.1 NZ_CP063780:c895358-895059 [Pseudomonas sp. OST1909]
MNHFKKSKPFQEWLDALRSEPARARILARLKNAQSGNFGDCEAVGNGVSEMRIHYGPGYRVYFIRRDEVIYLLLIGGDKS
TQKRDIQRAKQIAERFEKE

Download         Length: 300 bp

>T178829 NZ_CP084321:c5806163-5805864 [Pseudomonas aeruginosa]
ATGGTCGAAGTCAAACAAACCGCCACTTTCATGGCATGGGAAAGCAAGCTAAAGGATCGGCGGGCAAAGGCCGTGATCGC
CGCCCGTATCTTCCGATTGGCGAATGGACTACCCGGCGATGTGTCACCAGTCGGCCAGGGTGTGAGCGAGTTGAGGATTC
ACTATGGCCCAGGCTATCGGGTGTACTTCCAGCAGCGCGGGACGGAAATCGTCATCCTGCTATGTGGTGGAGACAAGAGC
AGCCAGGCCAGGGATATAGAAATGGCGAAACGCCTGGCAAATGAGTGGAGGCCGCAATGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10237.65 Da        Isoelectric Point: 4.4664

>AT178829 WP_005784366.1 NZ_CP063780:c895055-894768 [Pseudomonas sp. OST1909]
MTEFTDFDVAEHLKTPGDMAEYLEACFEEDAGDGLLIRSALNDIARAQGMTQVARDAGLGRESLYKALSSTGNPEFGTIM
KVMKALGLKLHATAI

Download         Length: 288 bp

>AT178829 NZ_CP084321:c5805867-5805577 [Pseudomonas aeruginosa]
ATGACCGAGCAAATTTATGATTATGACCCCGCGCAAGCGCTGGACAGCCCGGAGGCCATGGCTCTGTTCATCGCAGACGC
TTTGGATACTGGAGACACCGCCTATATCGCTAAGGCTATGGGAGTCGTGGCCCGCGCCAAGGGGATGACGGAGTTGGCCA
AGGAAACGGGTTTGGCCAGGGAGCAGCTTTACAAATCGTTTAGTGAGCGCGGGAACCCTACATTGAAAACCATGCTGGCA
GTAATGCGAGCTCTGGGAGTTGATCTGACCGCCCGCCCGCATGCTCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A7S7S4Q6

References