Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 516519..516787 Replicon chromosome
Accession NZ_CP063774
Organism Escherichia coli O25b:H4-ST131

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 516557..516659 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 516519..516787 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
INT78_RS02500 513677..515116 + 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
INT78_RS02505 515233..515469 + 237 WP_001295499.1 DUF1480 family protein -
INT78_RS02510 515574..515765 + 192 WP_001296140.1 YebW family protein -
INT78_RS02515 515766..516422 - 657 WP_000812745.1 protein-serine/threonine phosphatase -
- 516519..516787 + 269 - - Antitoxin
- 516557..516659 - 103 - - Toxin
INT78_RS02520 516817..517158 - 342 WP_000976472.1 YebY family protein -
INT78_RS02525 517171..518043 - 873 WP_000879317.1 copper homeostasis membrane protein CopD -
INT78_RS02530 518047..518421 - 375 WP_000168747.1 CopC domain-containing protein YobA -
INT78_RS02535 518560..518790 + 231 WP_000916763.1 DNA polymerase III subunit theta -
INT78_RS02540 518892..519548 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
INT78_RS02545 519572..520234 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T178787 NZ_CP063774:c516659-516557 [Escherichia coli O25b:H4-ST131]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT178787 NZ_CP063774:516519-516787 [Escherichia coli O25b:H4-ST131]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References