Detailed information of TA system TA178785

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tad-ata/COG5606-COG4679
• Location: 4737161..4737824
• Replicon: chromosome
• Accession: NZ_CP063773
• Organism: Pectobacterium carotovorum subsp. carotovorum PCCS1

Toxin (Protein)

• Gene name: tad
• Uniprot ID: -
• Locus tag: IQ281_RS21230
• Protein ID: WP_194430615.1
• Coordinates: 4737161..4737505 (+)
• Length: 115 a.a.

Antitoxin (Protein)

• Gene name: ata
• Uniprot ID: -
• Locus tag: IQ281_RS21235
• Protein ID: WP_194430617.1
• Coordinates: 4737507..4737824 (+)
• Length: 106 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IQ281_RS21205	4732732..4733862	+	1131	WP_194430605.1	linear amide C-N hydrolase	-
IQ281_RS21210	4733971..4734279	-	309	WP_194430607.1	hypothetical protein	-
IQ281_RS21215	4734297..4734926	-	630	WP_194430609.1	FMN-dependent NADH-azoreductase	-
IQ281_RS21220	4734961..4735734	-	774	WP_194430611.1	alpha/beta hydrolase	-
IQ281_RS21225	4735905..4736930	+	1026	WP_194430613.1	helix-turn-helix domain-containing protein	-
IQ281_RS21230	4737161..4737505	+	345	WP_194430615.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
IQ281_RS21235	4737507..4737824	+	318	WP_194430617.1	helix-turn-helix domain-containing protein	Antitoxin
IQ281_RS21240	4737911..4738126	-	216	WP_194430619.1	helix-turn-helix domain-containing protein	-
IQ281_RS21245	4738499..4738816	-	318	WP_194430621.1	hypothetical protein	-
IQ281_RS21250	4738833..4739147	-	315	WP_194430623.1	hypothetical protein	-
IQ281_RS21255	4739476..4741053	-	1578	WP_194430625.1	glutamine-hydrolyzing GMP synthase	-
IQ281_RS21260	4741161..4742627	-	1467	WP_015841181.1	IMP dehydrogenase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (12-105)

Antitoxin

• Cro/C1-type helix-turn-helix domain (34-86)

Sequences

Toxin

Protein

• Length: 115 a.a.
• Molecular weight: 12405.15 Da
• Isoelectric Point: 9.7825

>T178785 WP_194430615.1 NZ_CP063773:4737161-4737505 [Pectobacterium carotovorum subsp. carotovorum PCCS1]
MKSLYWVGSSKKDLQSLPADVQDVFGYALHMAQTGGKHTQAKPLKGFGGAGVLEVVEDYIGDTYRAVYTVKFGEAVYVLH
AFQKKSSSGIATPKPDMNTIRERLKTAENHAKGA

Nucleotide

• Length: 345 bp

>T178785 NZ_CP084290:c4507159-4506857 [Citrobacter werkmanii]
ATGTCTAAATCATTAAATATCAGAAATTTTCGGGATACATGGTTTGAAGATTTTTTTGAGCGGGCAACACCGCACAGAAA
AATACCCGCGGATATTCACACCGCATTAGCCAGAAAGCTGGATATCATCAATGCGGCGGTTTCGCATCGGGATTTGCGCT
CGCCGCCAGGGAATAGATATGAAGAGTTAACCGGAAAGTTACAGGAATATTCTTCAATAAGAGTAAATAAGCAGTACCGA
TTAATATTTAAATGGGTTAACGGTAAGGCCGAAGATGTGTACTTAGACCCACACATCTACTAG

Antitoxin

Protein

• Length: 106 a.a.
• Molecular weight: 11475.50 Da
• Isoelectric Point: 10.6133

>AT178785 WP_194430617.1 NZ_CP063773:4737507-4737824 [Pectobacterium carotovorum subsp. carotovorum PCCS1]
MSQDIEVSSGNVYADLGNLHAEDMLVKAQLATLINSIIKSRRLTQAEAAKLLGMPQPKLSNLLRGQFRGISETKMLECLT
KLGRDIQIVVGKPRRTPGSVKVVFA

Nucleotide

• Length: 318 bp

>AT178785 NZ_CP084290:c4506837-4506496 [Citrobacter werkmanii]
ATGAAACAGGCAACCAGAAAACCAACTACTGTGGGTGATGTCCTGCAATATGAATACCTGGAGCCGCTCGATCTGAAAAT
TAACGATCTAGCTGAAATACTGCATGTTCACCGTAATACGGTGAGCGCACTGGTCAATAATAATCGCAAATTAACAACGG
ATATGGCATTTCGCCTGGCGAAAGCGTTTGATACCTCCGTTGATTTCTGGCGTAACCTACAGTCGGCGGTTGACCTGTGG
GAAGTTGAAAATGATATGCGGGCGCAAGAAGAACTGAACCGTATTATGTCTGTTAAAGACTTTGTCGCGCAGCGAAATGT
CGCCACTAAGAAAGTCGCCTGA