Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 1808200..1808792 Replicon chromosome
Accession NZ_CP063773
Organism Pectobacterium carotovorum subsp. carotovorum PCCS1

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag IQ281_RS08205 Protein ID WP_181845790.1
Coordinates 1808200..1808454 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag IQ281_RS08210 Protein ID WP_181845791.1
Coordinates 1808451..1808792 (+) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IQ281_RS08195 1804582..1805133 + 552 WP_181845788.1 polymer-forming cytoskeletal protein -
IQ281_RS08200 1805170..1807890 + 2721 WP_194431475.1 CRISPR-associated helicase Cas3' -
IQ281_RS08205 1808200..1808454 + 255 WP_181845790.1 type II toxin-antitoxin system HicA family toxin Toxin
IQ281_RS08210 1808451..1808792 + 342 WP_181845791.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
IQ281_RS08215 1809361..1810935 + 1575 WP_194431476.1 type I-E CRISPR-associated protein Cse1/CasA -
IQ281_RS08220 1810919..1811551 + 633 WP_194431477.1 type I-E CRISPR-associated protein Cse2/CasB -
IQ281_RS08225 1811555..1812622 + 1068 WP_194431478.1 type I-E CRISPR-associated protein Cas7/Cse4/CasC -
IQ281_RS08230 1812632..1813366 + 735 WP_194431479.1 type I-E CRISPR-associated protein Cas5/CasD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(23-81)

Antitoxin

Uncharacterised protein family HicB

(55-100)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9554.01 Da        Isoelectric Point: 11.0200

>T178776 WP_181845790.1 NZ_CP063773:1808200-1808454 [Pectobacterium carotovorum subsp. carotovorum PCCS1]
MNKRHQKTLSDLFSRPVNGSIKWSDIESLFVALGAEIHEREGSRIAVLLQGEKKIFHRPHPRPTTDKGAVNSIRIWLESL
GVRP

Download         Length: 255 bp

>T178776 NZ_CP084288:71641-72972 [Caballeronia zhejiangensis]
ATCATGGCGCGCCGCACGCAATCCGGCCGACTCGACCTGTGGATGAACGGCCTGCCCGTCGGGCATTGGGAAACAGGCGC
GGCCGGCGAACGCCTCGTCTATCGCGACGACTGGATCGCCGATCCTCAAGGCCGTCCGCTATCGCTGTCGCTGCCCTTCA
CGCCGGGCAATCAGCCGTGGCGCGGGCAAGTCGTCACCGACTTCTTCGACAATCTCCTGCCCGATAGCGAGCCGATCCGC
CGCCGCATCGCCACGCGATTCCGCACCGGCGGCACGGCGCCGTTCCAGTTGCTCGCGCAGTTGGGCCGCGATTGCGTCGG
CGCCCTTCAAATGCTGCCGCCCGGCGAAGCGCCCGTCGATCTCGACACCATAAAAGGCCGTGCGCTCACCGCATCGCAGA
TCGCGCGTCTGTTACGCGAGACCACATCGGCGCCACAACTCGGTCAGCACGAAACGGTCGACGACCTGCGCCTGTCCATC
GCCGGGGCGCAGGAAAAGACCGCGCTTCTGCGTCACGGCAAGCGCTGGCTTCTGCCCGAAGGCAGCACGCCGACCACGCA
TATCTTCAAGCTGCCGCTCGGGCTCGTCGGCAACATGCGCGCCGACATGCGTACGTCGGTCGAGAACGAATGGCTCTGCT
CGAAGATCGTCGCGGCGTTCGGCCTGCCCATCGCGCGATGCGAAATGGAACGCTTCGACGATCAGAAGGTGCTCGTCGTC
GAGCGCTTCGATCGCCGTCTGTCGAGCGACAAATCGTGGATCCTGCGCCTGCCGCAAGAGGACATGTGTCAGGCCACCGG
CACGCCCGCGCTGCTCAAGTACGAGTCGGACGGCGGTCCCGGCATCGAACGGATCATGGAGGTGCTCGCCGGATCGACGC
ACGCCGCACAGGACCGTCTTCGCTTCTTTCGCACGCAGATGATCTTCTGGATACTCGCCGCCACCGATGGTCACGCGAAG
AACTTCAGCATCGCGCATCTGCCCGGCAACCGGTATGAATCGACGCCGCTTTATGACGTGCTCTCGGCGCATCCGGTCAT
CGGTACGCGGGCCAATCAATTCGCCGCGCAACGCGTGCGCCTCGCGATGGCCGTGCGCAGCAAGAACGCGCACTATCTGA
TCGGCGAGATTCAGCGGCGGCACTGGATCGCGCAGGGGCGGCGCGTGGGACTCGCCGCGAACGATGTCGAAACGAAGATC
GATGAACTCGGCGCGCGCACGCCGCACGTCATCGACGAAGTGGCCGCACGCTTGCCACGCGATTTCCCGATGGACGTCGC
CGAGACGATCTTCGACGGCATGCGCCGCCTCGCGCGCAAGCTCGCATCGTGA

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12358.99 Da        Isoelectric Point: 4.5805

>AT178776 WP_181845791.1 NZ_CP063773:1808451-1808792 [Pectobacterium carotovorum subsp. carotovorum PCCS1]
MINKLLIDGHPAVIAFDSEIEMFRGEFIGLNGGADFYAYSVDELKKEGATSLAIFLDECRRDGIEPYKSYSGKVTTRLTP
ERHAALAVAAQATGVSINELLNEGVDLVLERHS

Download         Length: 342 bp

>AT178776 NZ_CP084288:71300-71641 [Caballeronia zhejiangensis]
ATGGACTATTCGCTGAAAACACTGAGCCAGCTCAGGCCGATCCTGATCGGCTTTCGCAAGGCGGCGGGCCTTACGCAAGC
GGCGGTCGCGGCGCGTCTCGGCGTTACGCAGCAGACGTACGCGCAACTCGAAGCCAATCCGGCAGCAGTGAGCGTCGAAC
GTCTCTTCAAGGTTCTACGCGTGCTCGACGTGGAACTCGCGCTCACGCGAGCGGAAAAGGCGAGCGAAGCCACGCCGATA
CACCCGCCGCCGCCCATCGCGGCCAAGGCCACCGCCGCGCGCCCCGCACGCAAGCGCGCCACGGCCGCCGCTGCGGCCTC
GAAGAAACGGGAGAACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References