Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1467138..1467673 Replicon chromosome
Accession NZ_CP063773
Organism Pectobacterium carotovorum subsp. carotovorum PCCS1

Toxin (Protein)


Gene name relE Uniprot ID C6DJA0
Locus tag IQ281_RS06620 Protein ID WP_015842269.1
Coordinates 1467138..1467425 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q6DB37
Locus tag IQ281_RS06625 Protein ID WP_010281712.1
Coordinates 1467422..1467673 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IQ281_RS06605 1463760..1464488 - 729 WP_043881851.1 DUF1266 domain-containing protein -
IQ281_RS06610 1464707..1465549 + 843 WP_015842271.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
IQ281_RS06615 1465677..1467029 + 1353 WP_039474428.1 glutathione-disulfide reductase -
IQ281_RS06620 1467138..1467425 - 288 WP_015842269.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IQ281_RS06625 1467422..1467673 - 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IQ281_RS06630 1467928..1468833 + 906 WP_194431383.1 siderophore-interacting protein -
IQ281_RS06635 1468868..1469623 - 756 WP_181845543.1 thiol:disulfide interchange protein DsbG -
IQ281_RS06640 1469693..1470397 - 705 WP_194431384.1 SMI1/KNR4 family protein -
IQ281_RS06645 1470579..1471202 + 624 WP_194431385.1 LysE family translocator -
IQ281_RS06650 1471245..1472378 - 1134 WP_194431386.1 alkylhydroperoxidase domain protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11074.15 Da        Isoelectric Point: 10.3527

>T178774 WP_015842269.1 NZ_CP063773:c1467425-1467138 [Pectobacterium carotovorum subsp. carotovorum PCCS1]
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGMKDCYKIKLRASGFRLVYEVIDDVLIIAVVAVGK
RERSGVYHLASERMR

Download         Length: 288 bp

>T178774 NZ_CP084286:402880-403740 [Caballeronia zhejiangensis]
ATGAACATCCAGACGCTCGCGTGCTTTCCCGACACGCATATCGAAACCGCGCACGGCATCACGGGTTATCGCGAGGCAGG
TGCGATGCATCGGCGCGCGCTGCCCGTCGTGCTGCTGCATGGGATCGGGTCGGGCGCGGCGTCGTGGGTCCGGCAGCTCG
ACGCGCTCGGTGCGAAGCGGCGTGTCATCGCATGGGACGCGCCGGGGTATGGCGAATCTAGTTGCATACGTAACGATTCG
CCGCTTGCGCTCGATTACGGGCAAGCGTTGCGCGCGTGGCTCGATGCGCTCGATATCGATCGATGCGTGATCGTCGGCCA
TTCGCTCGGCGCGATCATCGCGGGATCATTCGCCGTGCATACGCCACAGCGCGTCGCGGGCCTGCTGCTGATATCGCCGG
CTGCGGGTTATGGCGCTGCATCGAAGGAAGTGCGCGAATCGAAACGCGATGCACGTTTGAAGATGCTGAACGAACTCGGC
CCGCAAGGACTCGCACGCGAGCGCAGCGCCAACATGCTTTCGCACTACGCCGACGATGAAGCGCGCGAATGGGTCCGCTG
GAACATGGCGCGCATCGTCCCCGCAGGCTATGCGCAAGCGACGCATCTGCTTGCCAACGCCGATCTCGCAGCGGATATCG
CGCGCTTTCACGGACGCATCGCGGTCGCCGTCGGCGCGGACGATGCGATCACGCCGCCCGACGCATGCGAGCGCATCGCG
CAGGCCGCGCGGGTCAATCTGCAAGTGATGCCGCGTGCGGGCCATGCAGGCTACGTCGAATCACCCGCTGCATACACCGC
ATTGATCGATGCGTTTTGCGAAAGCATCGAATCCCACACGAAAGACGGAGTACCGCAATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9117.47 Da        Isoelectric Point: 4.0637

>AT178774 WP_010281712.1 NZ_CP063773:c1467673-1467422 [Pectobacterium carotovorum subsp. carotovorum PCCS1]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Download         Length: 252 bp

>AT178774 NZ_CP084286:403737-404597 [Caballeronia zhejiangensis]
ATGACATCCCTCGCCACGGAAGAAGCCGACAAGGGCGAACCGACTTACATCGTGCCGGGACTCGAACGCGGATTGAAGAT
CCTCACCGAGTTCTCGCCGCGCGAACCGGTGCTTGGCGCGCCCGAATTGTCGCGACGCCTCGGCATTCCGCGCACGACGG
TTTTCCGCCTGTTGCAGACGCTCGAATCGCTCGGCTTTCTGGAGCGCGCGGACAAGGACCGCAACTATCGGCTGGGCGTC
GCCGTGCTGCGTCTCGGCTTCGAATATCTGAGCTCGCTTGAACTCACCGATCTCGGCCTGCCGATCATCGAAGCATTGCG
CGACGCGACCGGTCTCACGAGCCACATCCTCATTCGCGATGGCCGCGATGTCGTGTTCGTCGCGAAAGCGCAGAGTCACG
CGCCTATCTTCAGTTCGGTGAAGGTGAACGTCGGCACGCGCCTTCCCGCCCATGCGACGACGCACGGCCACGTTCTGATG
GGCGATCTTTCGCTCGATGAACTGCGCGCGCTCTATCCGGAAGCGCATCTCGAACGCTTCACGACGTCCACGCCCGAAAC
GGTCGAAGAGCTCTTCGAGCGCGTGAAGGAAGACGCCGAACGCGGCTACGCGACAAGCCAGTCGTCGTTCGAGCGCGGCA
TATCGGTCGTCACCGCGCCCGTTCGCAACGACACGGGACGCATCGTCGCCGTCATCACGACGACGATTCCGCGTCCCGAA
ATCGACGCAGCGTTGCTCGACAGCGGTCTCGTCGACAAGGTTCGCGAAGCCGCCGATGCGCTCTCGATGCGTCTCAACTA
TCGCCCGGGCGCGCGTGCGTCCGCGTCGAACCGCTACATGAAATCTCTGGGGTTGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3S0XQ75

Antitoxin

Source ID Structure
AlphaFold DB A0A0M2EZP0

References