Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/- |
Location | 662880..663521 | Replicon | chromosome |
Accession | NZ_CP063769 | ||
Organism | Acinetobacter sp. Ac-14 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | A0A009QSR1 |
Locus tag | IOD65_RS03230 | Protein ID | WP_005067287.1 |
Coordinates | 663132..663521 (+) | Length | 130 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | F0KQ03 |
Locus tag | IOD65_RS03225 | Protein ID | WP_014207740.1 |
Coordinates | 662880..663125 (+) | Length | 82 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IOD65_RS03205 | 658381..659388 | + | 1008 | WP_002116730.1 | DNA-directed RNA polymerase subunit alpha | - |
IOD65_RS03210 | 659407..659784 | + | 378 | WP_002049717.1 | 50S ribosomal protein L17 | - |
IOD65_RS03215 | 659966..661456 | + | 1491 | WP_005067285.1 | NAD(P)/FAD-dependent oxidoreductase | - |
IOD65_RS03220 | 661507..662679 | - | 1173 | WP_005067286.1 | acyl-CoA dehydrogenase family protein | - |
IOD65_RS03225 | 662880..663125 | + | 246 | WP_014207740.1 | succinate dehydrogenase assembly factor 2 | Antitoxin |
IOD65_RS03230 | 663132..663521 | + | 390 | WP_005067287.1 | hypothetical protein | Toxin |
IOD65_RS03235 | 664292..665380 | + | 1089 | WP_005067288.1 | hypothetical protein | - |
IOD65_RS03240 | 665464..666039 | + | 576 | WP_005067290.1 | rhombosortase | - |
IOD65_RS03245 | 666221..668416 | + | 2196 | WP_005067292.1 | TRAP transporter large permease subunit | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 130 a.a. Molecular weight: 15505.61 Da Isoelectric Point: 8.7390
>T178762 WP_005067287.1 NZ_CP063769:663132-663521 [Acinetobacter sp. Ac-14]
MIKELNFELKYSRVSVIFQLFVGLGLAILLYQLLTPIWWLCAVILLFIGFIFFLKQAQISQIEYLDQKLWSVAYFSKKEI
YRGEITKIIDYQLFVVIYLEETPTNIAIVWFDQLPIQQWKRLKVLEKLY
MIKELNFELKYSRVSVIFQLFVGLGLAILLYQLLTPIWWLCAVILLFIGFIFFLKQAQISQIEYLDQKLWSVAYFSKKEI
YRGEITKIIDYQLFVVIYLEETPTNIAIVWFDQLPIQQWKRLKVLEKLY
Download Length: 390 bp
>T178762 NZ_CP084250:683505-683684 [Caballeronia sp. Sq4a]
ATGAAGTACAGCGAGTTCAAAAGGTGGCTGCGCCAGCAAGGAGCCGAGTTCAAGCCGGCGAAAGGAAGCCATTTTCGCGT
GACCTTGCATGGAAGAACGACGATTTTCCCCGACCATGGAAGCAGGGAAATCGGTACCAAGCTAGTCGAACAGATCAAGA
AACAATTGGGATTGAAGTGA
ATGAAGTACAGCGAGTTCAAAAGGTGGCTGCGCCAGCAAGGAGCCGAGTTCAAGCCGGCGAAAGGAAGCCATTTTCGCGT
GACCTTGCATGGAAGAACGACGATTTTCCCCGACCATGGAAGCAGGGAAATCGGTACCAAGCTAGTCGAACAGATCAAGA
AACAATTGGGATTGAAGTGA
Antitoxin
Download Length: 82 a.a. Molecular weight: 9833.26 Da Isoelectric Point: 4.7037
>AT178762 WP_014207740.1 NZ_CP063769:662880-663125 [Acinetobacter sp. Ac-14]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVDQEDPDLLDWFMEVSEPPRTELREFIYKLKQYVH
G
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVDQEDPDLLDWFMEVSEPPRTELREFIYKLKQYVH
G
Download Length: 246 bp
>AT178762 NZ_CP084250:683720-684139 [Caballeronia sp. Sq4a]
ATGTTGTCCTATCCAGTCAACCTGGAGCTCGATACGAACAACAGCTACCTGGTGACGTTCCCCGACATTCCGGAAGCGGT
GTCGGTAGGCGACGATAAAGAGGAGGCGCTCTTGAATGCGCTGGATGCGCTCGAAAGCGCCATCGAGATCTACTTCAATG
AGAAACGCGAATTGCCGCCTCCGTCGAAGCCGCGCAAGGGCCAGGCCGTCGTTACGTTGCCGGCGCTCGTCGTCTCGAAG
GTTCTACTGGCTAACGAAATGGTGCGGCAAGGCGTGCGAAAGTCGGAGCTCGCGCGTCGGCTCAATGTTCACATGCCGCA
GGTGGACCGGCTGCTGAATCCGCGTCATCCGTCAAAACTCGACGCTATCGAAGCCGCATTGAAATCGCTGGGCAAGCGCC
TCAGCATTTCTCTCGCGTAG
ATGTTGTCCTATCCAGTCAACCTGGAGCTCGATACGAACAACAGCTACCTGGTGACGTTCCCCGACATTCCGGAAGCGGT
GTCGGTAGGCGACGATAAAGAGGAGGCGCTCTTGAATGCGCTGGATGCGCTCGAAAGCGCCATCGAGATCTACTTCAATG
AGAAACGCGAATTGCCGCCTCCGTCGAAGCCGCGCAAGGGCCAGGCCGTCGTTACGTTGCCGGCGCTCGTCGTCTCGAAG
GTTCTACTGGCTAACGAAATGGTGCGGCAAGGCGTGCGAAAGTCGGAGCTCGCGCGTCGGCTCAATGTTCACATGCCGCA
GGTGGACCGGCTGCTGAATCCGCGTCATCCGTCAAAACTCGACGCTATCGAAGCCGCATTGAAATCGCTGGGCAAGCGCC
TCAGCATTTCTCTCGCGTAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A009QSR1 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | F0KQ03 |