Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 662880..663521 Replicon chromosome
Accession NZ_CP063769
Organism Acinetobacter sp. Ac-14

Toxin (Protein)


Gene name cptA Uniprot ID A0A009QSR1
Locus tag IOD65_RS03230 Protein ID WP_005067287.1
Coordinates 663132..663521 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID F0KQ03
Locus tag IOD65_RS03225 Protein ID WP_014207740.1
Coordinates 662880..663125 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IOD65_RS03205 658381..659388 + 1008 WP_002116730.1 DNA-directed RNA polymerase subunit alpha -
IOD65_RS03210 659407..659784 + 378 WP_002049717.1 50S ribosomal protein L17 -
IOD65_RS03215 659966..661456 + 1491 WP_005067285.1 NAD(P)/FAD-dependent oxidoreductase -
IOD65_RS03220 661507..662679 - 1173 WP_005067286.1 acyl-CoA dehydrogenase family protein -
IOD65_RS03225 662880..663125 + 246 WP_014207740.1 succinate dehydrogenase assembly factor 2 Antitoxin
IOD65_RS03230 663132..663521 + 390 WP_005067287.1 hypothetical protein Toxin
IOD65_RS03235 664292..665380 + 1089 WP_005067288.1 hypothetical protein -
IOD65_RS03240 665464..666039 + 576 WP_005067290.1 rhombosortase -
IOD65_RS03245 666221..668416 + 2196 WP_005067292.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15505.61 Da        Isoelectric Point: 8.7390

>T178762 WP_005067287.1 NZ_CP063769:663132-663521 [Acinetobacter sp. Ac-14]
MIKELNFELKYSRVSVIFQLFVGLGLAILLYQLLTPIWWLCAVILLFIGFIFFLKQAQISQIEYLDQKLWSVAYFSKKEI
YRGEITKIIDYQLFVVIYLEETPTNIAIVWFDQLPIQQWKRLKVLEKLY

Download         Length: 390 bp

>T178762 NZ_CP084250:683505-683684 [Caballeronia sp. Sq4a]
ATGAAGTACAGCGAGTTCAAAAGGTGGCTGCGCCAGCAAGGAGCCGAGTTCAAGCCGGCGAAAGGAAGCCATTTTCGCGT
GACCTTGCATGGAAGAACGACGATTTTCCCCGACCATGGAAGCAGGGAAATCGGTACCAAGCTAGTCGAACAGATCAAGA
AACAATTGGGATTGAAGTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9833.26 Da        Isoelectric Point: 4.7037

>AT178762 WP_014207740.1 NZ_CP063769:662880-663125 [Acinetobacter sp. Ac-14]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVDQEDPDLLDWFMEVSEPPRTELREFIYKLKQYVH
G

Download         Length: 246 bp

>AT178762 NZ_CP084250:683720-684139 [Caballeronia sp. Sq4a]
ATGTTGTCCTATCCAGTCAACCTGGAGCTCGATACGAACAACAGCTACCTGGTGACGTTCCCCGACATTCCGGAAGCGGT
GTCGGTAGGCGACGATAAAGAGGAGGCGCTCTTGAATGCGCTGGATGCGCTCGAAAGCGCCATCGAGATCTACTTCAATG
AGAAACGCGAATTGCCGCCTCCGTCGAAGCCGCGCAAGGGCCAGGCCGTCGTTACGTTGCCGGCGCTCGTCGTCTCGAAG
GTTCTACTGGCTAACGAAATGGTGCGGCAAGGCGTGCGAAAGTCGGAGCTCGCGCGTCGGCTCAATGTTCACATGCCGCA
GGTGGACCGGCTGCTGAATCCGCGTCATCCGTCAAAACTCGACGCTATCGAAGCCGCATTGAAATCGCTGGGCAAGCGCC
TCAGCATTTCTCTCGCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A009QSR1

Antitoxin

Source ID Structure
AlphaFold DB F0KQ03

References