Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 2180691..2181250 Replicon chromosome
Accession NZ_CP063658
Organism Lysobacter sp. H23M47

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag INQ43_RS09890 Protein ID WP_194036324.1
Coordinates 2180691..2181005 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag INQ43_RS09895 Protein ID WP_194036325.1
Coordinates 2180993..2181250 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
INQ43_RS09870 2175896..2177116 - 1221 WP_194036321.1 cystathionine gamma-synthase -
INQ43_RS09875 2177113..2178174 - 1062 WP_194036322.1 homoserine O-succinyltransferase -
INQ43_RS09880 2178490..2179626 + 1137 WP_194036323.1 phytase -
INQ43_RS09885 2179656..2180540 + 885 WP_194037650.1 peptidoglycan DD-metalloendopeptidase family protein -
INQ43_RS09890 2180691..2181005 - 315 WP_194036324.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
INQ43_RS09895 2180993..2181250 - 258 WP_194036325.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
INQ43_RS09900 2181618..2182049 + 432 WP_194036326.1 pilin -
INQ43_RS09905 2182597..2183040 + 444 WP_194036327.1 hypothetical protein -
INQ43_RS09910 2183151..2183441 + 291 WP_194036328.1 transcriptional regulator -
INQ43_RS09915 2183726..2185456 + 1731 WP_194036329.1 type IV-A pilus assembly ATPase PilB -
INQ43_RS09920 2185550..2185855 + 306 WP_194036330.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11827.56 Da        Isoelectric Point: 7.1643

>T178678 WP_194036324.1 NZ_CP063658:c2181005-2180691 [Lysobacter sp. H23M47]
MAEIVWTAPALSDLDAIADYIALEDPVAASELVKRVLAHVEQLADHPESGSRPAELGRSRYRQVVEPPCRVFYRYDGQTV
FVLYVMRTERLLRKAQLTSRTPQK

Download         Length: 315 bp

>T178678 NZ_CP084207:4404137-4404415 [Escherichia coli]
ATGATTCAAAGGGATATTGAATACTCGGGACAATATTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAA
TAAATTGAAATATCTTATGACGCTTCTTATCAATAATACTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAG
GTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGA
TTTGAGAGAACTGGAACTCACGCGGCGCTCTTTGGGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9757.32 Da        Isoelectric Point: 9.7761

>AT178678 WP_194036325.1 NZ_CP063658:c2181250-2180993 [Lysobacter sp. H23M47]
MRTELVTTLKRQATELLSDIERDKEPILITQHGLPSAYLVDVESYQLMQQRMAVLEGIARGEQAIAESRVVTHAQARKRL
ARWLK

Download         Length: 258 bp

>AT178678 NZ_CP084207:4403874-4404134 [Escherichia coli]
ATGGCTGCTAACGCGTTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCAGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCATTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References