Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3128195..3128466 Replicon chromosome
Accession NZ_CP063511
Organism Escherichia coli strain EH08-18-36

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3128325..3128428 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3128195..3128466 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IQS18_RS15145 3124750..3125412 - 663 WP_000944258.1 exodeoxyribonuclease X -
IQS18_RS15150 3125436..3126092 - 657 WP_001752600.1 carbon-nitrogen hydrolase family protein -
IQS18_RS15155 3126194..3126424 - 231 WP_000916763.1 DNA polymerase III subunit theta -
IQS18_RS15160 3126563..3126937 + 375 WP_000168747.1 CopC domain-containing protein YobA -
IQS18_RS15165 3126941..3127813 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
IQS18_RS15170 3127826..3128167 + 342 WP_000976472.1 YebY family protein -
- 3128195..3128466 - 272 - - Antitoxin
- 3128325..3128428 + 104 - - Toxin
IQS18_RS15175 3128563..3129219 + 657 WP_001752599.1 protein-serine/threonine phosphatase -
IQS18_RS15180 3129220..3129411 - 192 WP_001338167.1 YebW family protein -
IQS18_RS15185 3129516..3129752 - 237 WP_001338166.1 DUF1480 family protein -
IQS18_RS15190 3129870..3131309 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T178585 NZ_CP063511:3128325-3128428 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT178585 NZ_CP063511:c3128466-3128195 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References