Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3575224..3575495 Replicon chromosome
Accession NZ_CP063492
Organism Escherichia coli strain EF5-18-41

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3575262..3575365 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3575224..3575495 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IQS14_RS17365 3572381..3573820 + 1440 WP_001309555.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
IQS14_RS17370 3573938..3574174 + 237 WP_001295499.1 DUF1480 family protein -
IQS14_RS17375 3574279..3574470 + 192 WP_001296140.1 YebW family protein -
IQS14_RS17380 3574471..3575127 - 657 WP_000812712.1 protein-serine/threonine phosphatase -
- 3575224..3575495 + 272 - - Antitoxin
- 3575262..3575365 - 104 - - Toxin
IQS14_RS17385 3575523..3575864 - 342 WP_000976481.1 YebY family protein -
IQS14_RS17390 3575877..3576749 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
IQS14_RS17395 3576753..3577127 - 375 WP_000204705.1 CopC domain-containing protein YobA -
IQS14_RS17400 3577266..3577496 + 231 WP_000916763.1 DNA polymerase III subunit theta -
IQS14_RS17405 3577598..3578254 + 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
IQS14_RS17410 3578278..3578940 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3559385..3584668 25283


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T178489 NZ_CP063492:c3575365-3575262 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT178489 NZ_CP063492:3575224-3575495 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References