Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | yjhX-yjhQ/YjhX-GNAT |
| Location | 334194..335014 | Replicon | chromosome |
| Accession | NZ_CP063459 | ||
| Organism | Escherichia coli strain EM22-18-53 | ||
Toxin (Protein)
| Gene name | yjhX | Uniprot ID | B6I030 |
| Locus tag | IQS26_RS01540 | Protein ID | WP_001054379.1 |
| Coordinates | 334194..334451 (+) | Length | 86 a.a. |
Antitoxin (Protein)
| Gene name | yjhQ | Uniprot ID | - |
| Locus tag | IQS26_RS01545 | Protein ID | WP_000123957.1 |
| Coordinates | 334463..335014 (+) | Length | 184 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IQS26_RS01520 | 329481..330587 | + | 1107 | WP_001295733.1 | N-acetylneuraminate epimerase | - |
| IQS26_RS01525 | 330651..331631 | + | 981 | WP_000991462.1 | 9-O-acetyl-N-acetylneuraminic acid deacetylase | - |
| IQS26_RS01530 | 332214..333440 | - | 1227 | Protein_297 | DNA helicase | - |
| IQS26_RS01535 | 333518..333817 | + | 300 | WP_001332034.1 | GNAT family N-acetyltransferase | - |
| IQS26_RS01540 | 334194..334451 | + | 258 | WP_001054379.1 | YjhX family toxin | Toxin |
| IQS26_RS01545 | 334463..335014 | + | 552 | WP_000123957.1 | N-acetyltransferase | Antitoxin |
| IQS26_RS01550 | 335066..335812 | + | 747 | WP_001588380.1 | class I SAM-dependent methyltransferase | - |
| IQS26_RS01555 | 335940..336200 | + | 261 | WP_000077646.1 | hypothetical protein | - |
| IQS26_RS01560 | 336238..336354 | + | 117 | Protein_303 | VOC family protein | - |
| IQS26_RS01565 | 336599..337720 | + | 1122 | WP_000010833.1 | M42 family metallopeptidase | - |
| IQS26_RS01570 | 337717..337995 | + | 279 | WP_000722973.1 | PTS sugar transporter subunit IIB | - |
| IQS26_RS01575 | 338007..339320 | + | 1314 | WP_000460845.1 | galactitol-specific PTS transporter subunit IIC | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | fimE / fimB | 325615..343235 | 17620 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9568.07 Da Isoelectric Point: 11.1381
>T178272 WP_001054379.1 NZ_CP063459:334194-334451 [Escherichia coli]
MNLSRQEQRTLHVLAKGGRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR
MNLSRQEQRTLHVLAKGGRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR
Download Length: 258 bp
>T178272 NZ_CP083890:c28195-28043 [Escherichia coli]
ATGCCACAGCGAACGTTTTTAATGATGTTAATCGTCATCTGTGTGACGATTCTGTGTTTTGTCTGGATGGTGAGGGATTC
GCTTTGCGTACTCCGGCTCCAGCAGGGAAACACAGTGCTTGTGGCAACGTTAGCCTACGAAGTTAAACGTTAA
ATGCCACAGCGAACGTTTTTAATGATGTTAATCGTCATCTGTGTGACGATTCTGTGTTTTGTCTGGATGGTGAGGGATTC
GCTTTGCGTACTCCGGCTCCAGCAGGGAAACACAGTGCTTGTGGCAACGTTAGCCTACGAAGTTAAACGTTAA
Antitoxin
Download Length: 184 a.a. Molecular weight: 20358.34 Da Isoelectric Point: 6.4182
>AT178272 WP_000123957.1 NZ_CP063459:334463-335014 [Escherichia coli]
MTAHHFTFQITDESDASDIREVETRAFGFSKEADLTASLLEDESARPALSLLARHEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQALTA
QPMNVTGHIQCAQALMKPEHWRE
MTAHHFTFQITDESDASDIREVETRAFGFSKEADLTASLLEDESARPALSLLARHEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQALTA
QPMNVTGHIQCAQALMKPEHWRE
Download Length: 552 bp
>AT178272 NZ_CP083890:28245-28307 [Escherichia coli]
TCGAAGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
TCGAAGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|