Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1879499..1880103 Replicon chromosome
Accession NZ_CP063455
Organism Pseudomonas protegens strain PC-578039

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag IP586_RS08715 Protein ID WP_123393354.1
Coordinates 1879804..1880103 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag IP586_RS08710 Protein ID WP_103741196.1
Coordinates 1879499..1879807 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IP586_RS08690 1874678..1875277 + 600 WP_102861686.1 FMN-dependent NADH-azoreductase -
IP586_RS08695 1875523..1876386 + 864 WP_123393356.1 carboxylate/amino acid/amine transporter -
IP586_RS08700 1876580..1877878 - 1299 WP_115581831.1 mechanosensitive ion channel family protein -
IP586_RS08705 1878072..1879412 + 1341 WP_042941946.1 DEAD/DEAH box helicase -
IP586_RS08710 1879499..1879807 - 309 WP_103741196.1 putative addiction module antidote protein Antitoxin
IP586_RS08715 1879804..1880103 - 300 WP_123393354.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IP586_RS08720 1880445..1882166 + 1722 WP_267270025.1 ShlB/FhaC/HecB family hemolysin secretion/activation protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(5-96)

Antitoxin

Uncharacterized protein HI1420

(5-95)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 10889.53 Da        Isoelectric Point: 10.7639

>T178262 WP_123393354.1 NZ_CP063455:c1880103-1879804 [Pseudomonas protegens]
MKYLIQQTQSFARWHSSLKDLRAKISIARRIDRAATGNLGDVKSVGEGISELRVDVGPGYRLYFTQRGGVIIVLLAGGDK
SSQDADIRRAKILAKDLST

Download         Length: 300 bp

>T178262 NZ_CP083888:2730544-2730651 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11119.70 Da        Isoelectric Point: 5.6015

>AT178262 WP_103741196.1 NZ_CP063455:c1879807-1879499 [Pseudomonas protegens]
MTQILTHFDMAELLDSDQAIAEYLSQVLADGDTEEFLRAIGYVAKARGMSQIARDAGMGRESLYKAFAPGSKPRFDTVLK
VIHALGIDLQAQPGHVEKPKAS

Download         Length: 309 bp

>AT178262 NZ_CP083888:c2730491-2730430 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References