178260

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 920054..920650 Replicon chromosome
Accession NZ_CP063455
Organism Pseudomonas protegens strain PC-578039

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IP586_RS04220 Protein ID WP_267269308.1
Coordinates 920348..920650 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IP586_RS04215 Protein ID WP_102881959.1
Coordinates 920054..920344 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IP586_RS04195 916326..918458 - 2133 WP_267269305.1 TonB-dependent copper receptor -
IP586_RS04200 918547..918993 - 447 WP_267269306.1 DUF2946 domain-containing protein -
IP586_RS04205 919012..919491 - 480 WP_180988479.1 copper chaperone PCu(A)C -
IP586_RS04210 919556..919954 - 399 WP_267269307.1 DUF2946 domain-containing protein -
IP586_RS04215 920054..920344 - 291 WP_102881959.1 putative addiction module antidote protein Antitoxin
IP586_RS04220 920348..920650 - 303 WP_267269308.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IP586_RS04225 920833..921561 - 729 WP_213664658.1 cobalt-precorrin-6A reductase -
IP586_RS04230 921558..922655 - 1098 WP_267269309.1 cobalt-precorrin-5B (C(1))-methyltransferase -
IP586_RS04235 922749..923963 - 1215 WP_123391215.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
IP586_RS04240 924065..925408 + 1344 WP_258379198.1 precorrin-3B synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-97)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11508.18 Da        Isoelectric Point: 10.4257

>T178260 WP_267269308.1 NZ_CP063455:c920650-920348 [Pseudomonas protegens]
MFVFEQTQAFTHWLLSLKDPQGKTRVLARIRAAQLGRFGDCEPVGEGVYEMRIHRGPGYRGYFSRRDTVIYLLLIGGDKG
TQRRDIQRARQLAHDLKSEG

Download         Length: 303 bp

>T178260 NZ_CP083888:2380735-2382057 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCCAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CAGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCTAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTAACGTTATTACCCGAAAA
TGAAACCATAACGCGCCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGGCTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCTCTGGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCGCAGGAGAAGACAGCGCTG
CTTAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAGGGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATACTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCTGTAAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCGTTTTTGATGGGGTCCAGCGAGGCGCTTCGCGATCGTTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGATGGCCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTAAGTGACTTTGCCAGAATGATTCCG
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10429.01 Da        Isoelectric Point: 6.9783

>AT178260 WP_102881959.1 NZ_CP063455:c920344-920054 [Pseudomonas protegens]
MRTPVTRFDAAEYLKTPEDMVAYLDACFEEDAGDGKLIRAALNDIARARGMTQVARDTGLGRESLYKALGSQGNPEFATI
IKVMKALGLKLHVSPA

Download         Length: 291 bp

>AT178260 NZ_CP083888:2380469-2380735 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTAGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGCATTAAGCAGGCGACAATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACACTATGCGACACGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAGATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References