Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 666686..667251 Replicon chromosome
Accession NZ_CP063450
Organism Rhodococcus pyridinivorans strain 5Ap

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag INP59_RS03160 Protein ID WP_193903834.1
Coordinates 667006..667251 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag INP59_RS03155 Protein ID WP_006551856.1
Coordinates 666686..666976 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
INP59_RS03130 661919..662521 + 603 WP_138845417.1 TetR/AcrR family transcriptional regulator -
INP59_RS03135 662518..662946 + 429 WP_193903077.1 HIT family protein -
INP59_RS03140 662951..664552 + 1602 WP_193903078.1 L-lactate permease -
INP59_RS03145 664629..665657 + 1029 WP_064255975.1 Dyp-type peroxidase -
INP59_RS03150 665654..666472 + 819 WP_006551857.1 bacteriocin family protein -
INP59_RS03155 666686..666976 + 291 WP_006551856.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
INP59_RS03160 667006..667251 + 246 WP_193903834.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
INP59_RS03165 667308..667787 - 480 WP_064255973.1 MarR family transcriptional regulator -
INP59_RS03170 667846..668595 - 750 WP_024102983.1 cutinase family protein -
INP59_RS03175 668745..669407 - 663 WP_024102984.1 alpha-ketoglutarate-dependent dioxygenase AlkB -
INP59_RS03180 669528..670358 + 831 WP_006551851.1 SDR family oxidoreductase -
INP59_RS03185 670403..671374 + 972 WP_006551850.1 phosphotriesterase -
INP59_RS03190 671411..672130 - 720 WP_193903079.1 2OG-Fe(II) oxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(29-80)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-73)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 8943.27 Da        Isoelectric Point: 10.3368

>T178253 WP_193903834.1 NZ_CP063450:667006-667251 [Rhodococcus pyridinivorans]
MARSAARAMARSLPEKVATAVYEFVTGPLLENPKRVGKPLNPPLAPAYSARRGEYRALYLIDDANRTVEVTAISHRADAY
R

Download         Length: 246 bp

>T178253 NZ_CP083888:868929-869336 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10788.92 Da        Isoelectric Point: 4.2336

>AT178253 WP_006551856.1 NZ_CP063450:666686-666976 [Rhodococcus pyridinivorans]
MYMTTLPVADARAQLSRLVDEAERTHERFEITRNGHRAAVLLGADDYDAMQETIAVLSDTDLLRAHVEGRTEVESGDVVD
VQELTQLMRDARSSEE

Download         Length: 291 bp

>AT178253 NZ_CP083888:868682-868948 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References