Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RHH
Location 1317301..1317858 Replicon chromosome
Accession NZ_CP063425
Organism Kosakonia pseudosacchari strain BDA62-3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IP581_RS06070 Protein ID WP_086871382.1
Coordinates 1317301..1317576 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IP581_RS06075 Protein ID WP_086871384.1
Coordinates 1317586..1317858 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IP581_RS06045 1312873..1313286 + 414 WP_193821994.1 proofreading thioesterase EntH -
IP581_RS06050 1313455..1315560 + 2106 WP_193821995.1 carbon starvation protein CstA -
IP581_RS06055 1315581..1315778 + 198 WP_017455812.1 YbdD/YjiX family protein -
IP581_RS06060 1315832..1316575 - 744 WP_086871376.1 3-oxoacyl-ACP reductase FabG -
IP581_RS06065 1316686..1317273 + 588 WP_086871380.1 TetR/AcrR family transcriptional regulator -
IP581_RS06070 1317301..1317576 - 276 WP_086871382.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IP581_RS06075 1317586..1317858 - 273 WP_086871384.1 ribbon-helix-helix protein, CopG family Antitoxin
IP581_RS06080 1317963..1319993 - 2031 WP_193821996.1 choline transporter -
IP581_RS06085 1320233..1320829 + 597 WP_044489591.1 transcriptional regulator BetI -
IP581_RS06090 1320842..1322314 + 1473 WP_193821997.1 betaine-aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10626.40 Da        Isoelectric Point: 5.1007

>T178203 WP_086871382.1 NZ_CP063425:c1317576-1317301 [Kosakonia pseudosacchari]
MQLEWTLLALQDIERLSRFLFLKNPEAARKVVAMLADAPEMLLLHPQIGPADDAFSPRDVRSLFVGSYEMIYELTDTRII
ILRVWHTKEDR

Download         Length: 276 bp

>T178203 NZ_CP083880:c52229-51852 [Escherichia coli]
ATGAAAACATTACCCGATACACACGTACGGGAGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCATTACGGCCTTACGCTGAATGACACACCGTTCGCCGATGAACGTGTGATTGAGCAGCATATTG
AAGCTGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTACGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGGCCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAACATCCGGGGGCGAAACAATGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10034.53 Da        Isoelectric Point: 7.0152

>AT178203 WP_086871384.1 NZ_CP063425:c1317858-1317586 [Kosakonia pseudosacchari]
MPETKVLTAHVPIELAQKVDLLAESSERSRGWIIKRALAEYVERAELRQSMIQQGLEAVERGETLSNAEATNWLKSLGTA
NPLPLPTPRK

Download         Length: 273 bp

>AT178203 NZ_CP083880:c52687-52319 [Escherichia coli]
GTGTCAGACACATTCTCCGGGACAACGCATCCCGATGACAATCACGACCGCCCCTGGTGGGGGCTGCCCTGTACCGTGAC
ACCTTGTTTTGGCGCCCGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCGGATGCATACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCTAAAGGGCTGACCTGCGATGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACCCCCGAAACGAAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References