Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 668291..668855 Replicon chromosome
Accession NZ_CP063425
Organism Kosakonia pseudosacchari strain BDA62-3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IP581_RS03095 Protein ID WP_193821735.1
Coordinates 668550..668855 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IP581_RS03090 Protein ID WP_086870332.1
Coordinates 668291..668563 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IP581_RS03060 663326..664096 - 771 WP_097401174.1 AraC family transcriptional regulator -
IP581_RS03065 664139..665035 - 897 WP_097401176.1 LysR family transcriptional regulator -
IP581_RS03070 665413..666096 + 684 WP_193821733.1 hypothetical protein -
IP581_RS03075 666089..666556 + 468 WP_193821734.1 YjiG family protein -
IP581_RS03080 666574..667677 + 1104 WP_097401178.1 M20 peptidase aminoacylase family protein -
IP581_RS03085 667679..668194 - 516 WP_086870330.1 VOC family protein -
IP581_RS03090 668291..668563 + 273 WP_086870332.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
IP581_RS03095 668550..668855 + 306 WP_193821735.1 type II toxin-antitoxin system YafQ family toxin Toxin
IP581_RS03100 669251..670621 + 1371 WP_193821736.1 NAD-dependent succinate-semialdehyde dehydrogenase -
IP581_RS03105 670665..671621 - 957 WP_086870338.1 GTPase -
IP581_RS03110 671632..671835 - 204 WP_007373011.1 YbdD/YjiX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(11-101)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-85)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11516.18 Da        Isoelectric Point: 8.0750

>T178201 WP_193821735.1 NZ_CP063425:668550-668855 [Kosakonia pseudosacchari]
MGKSKRAPLPYRSDYTKTFIKACERYNRAGRRDMHETAAIMSLILSGNPLPAQYNDHALTGDMVGFRELHIGGDYLLVYR
VDKDKHLVVFTDIGTHAELFE

Download         Length: 306 bp

>T178201 NZ_CP083878:119777-120052 [Escherichia coli]
ATGGAACTGAAGTGGACCAGTAAGGCGCTTTCTGATTTGTCGCGGTTATTTGATTTTCTGGTGCTGGCCAGTAAACCTGC
TGCCGCCAGAACGGTACAGTCCCTGACACAGGCACCGGTCATTCTGTTAACTCATCCACGTATGGGAGAACAGTTGTTTC
AGTTTGAACCCAGGGAGGTCAGACGGATTTTTGCTGGCGAGTACGAAATCCGTTACGAAATTAATGGCCAGACTATTTAT
GTATTGCGTCTGTGGCACACACGAGAAAACAGGTAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10078.45 Da        Isoelectric Point: 5.8481

>AT178201 WP_086870332.1 NZ_CP063425:668291-668563 [Kosakonia pseudosacchari]
MDSIIRSRINSDLKARAGSVLESCGLNWSTAIRLFAEQIVKTEGIPFEVTRKPTARLRKAMTETEDILAHQNGRFDGIDQ
LMDSLNDGKE

Download         Length: 273 bp

>AT178201 NZ_CP083878:119493-119777 [Escherichia coli]
ATGCAAATGAAAAACAATGCCGCACAAGCAACAAAAGTAATTACCGCGCATGTGCCATTACCTATGGCTGATAAAGTCGA
CCAGATGGCCGCCAGACTGGAACGTTCCCGGGGCTGGGTTATCAAACAGGCGCTTTCTGCATGGCTTGCCCAGGAGGAGG
AGCGTAATCGCCTGACGCTGGAAGCCCTGGACGATGTGACATCCGGACAGGTTATCGACCATCAGGCTGTACAGGCCTGG
TCGGACAGCCTCAGTACTGACAATCCGTTACCGGTGCCACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References