Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 757778..758337 Replicon chromosome
Accession NZ_CP063418
Organism Actinomyces sp. ZJ34

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HRL51_RS03060 Protein ID WP_172119570.1
Coordinates 757778..758074 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HRL51_RS03065 Protein ID WP_172193329.1
Coordinates 758074..758337 (-) Length 88 a.a.

Genomic Context

HRL51_RS03045HRL51_RS03050HRL51_RS03055HRL51_RS03080HRL51_RS03085HRL51_RS03035HRL51_RS03040HRL51_RS03060HRL51_RS03065HRL51_RS03070HRL51_RS03075HRL51_RS03090HRL51_RS03095
Location: 755973..756236 (264 bp)
Type: Others
Protein ID: WP_172193325.1
Location: 756323..756730 (408 bp)
Type: Others
Protein ID: WP_172193327.1
Location: 756699..757478 (780 bp)
Type: Others
Protein ID: WP_172119571.1
Location: 760109..760336 (228 bp)
Type: Others
Protein ID: WP_172193333.1
Location: 760320..760577 (258 bp)
Type: Others
Protein ID: WP_172193334.1
Location: 753270..755027 (1758 bp)
Type: Others
Protein ID: WP_172193321.1
Location: 755024..755455 (432 bp)
Type: Others
Protein ID: WP_172193323.1
Location: 757778..758074 (297 bp)
Type: Toxin
Protein ID: WP_172119570.1
Location: 758074..758337 (264 bp)
Type: Antitoxin
Protein ID: WP_172193329.1
Location: 758469..759512 (1044 bp)
Type: Others
Protein ID: WP_172193386.1
Location: 759548..759916 (369 bp)
Type: Others
Protein ID: WP_172193331.1
Location: 760698..760907 (210 bp)
Type: Others
Protein ID: WP_172193336.1
Location: 762212..763039 (828 bp)
Type: Others
Protein ID: WP_172193338.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HRL51_RS03035753270..755027-1758WP_172193321.1relaxase/mobilization nuclease domain-containing protein-
HRL51_RS03040755024..755455-432WP_172193323.1plasmid mobilization relaxosome protein MobC-
HRL51_RS03045755973..756236+264WP_172193325.1hypothetical protein-
HRL51_RS03050756323..756730+408WP_172193327.1DNA-processing protein DprA-
HRL51_RS03055756699..757478+780WP_172119571.1DUF3800 domain-containing protein-
HRL51_RS03060757778..758074-297WP_172119570.1type II toxin-antitoxin system YafQ family toxinToxin
HRL51_RS03065758074..758337-264WP_172193329.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
HRL51_RS03070758469..759512-1044WP_172193386.1lytic transglycosylase domain-containing protein-
HRL51_RS03075759548..759916-369WP_172193331.1hypothetical protein-
HRL51_RS03080760109..760336+228WP_172193333.1ribbon-helix-helix protein, CopG family-
HRL51_RS03085760320..760577+258WP_172193334.1type II toxin-antitoxin system RelE/ParE family toxin-
HRL51_RS03090760698..760907-210WP_172193336.1hypothetical protein-
HRL51_RS03095762212..763039-828WP_172193338.1tyrosine-type recombinase/integrase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(9-96)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-78)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11249.77 Da        Isoelectric Point: 7.1297

>T178176 WP_172119570.1 NZ_CP063418:c758074-757778 [Actinomyces sp. ZJ34]
MVLAPEPTPRFRRDVKALRKKHVDLAPLREVIDLIVADTDQARDELVRHHGMHRLRGQWEASNECHVANAGDWLLIWTTT
QTQAILQRTGGHDDLFGH

Download         Length: 297 bp

>T178176 NZ_CP083872:c4124474-4124124 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GTGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTT
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9779.95 Da        Isoelectric Point: 4.3988

>AT178176 WP_172193329.1 NZ_CP063418:c758337-758074 [Actinomyces sp. ZJ34]
MATITVRVEDSVKEGVTQIAEDFGFDLSSVTRAFYLQMIREHRIPLNLSYPQPSAASREAIEQTRQIIASGQHTYDTAEA
MYEDLGL

Download         Length: 264 bp

>AT178176 NZ_CP083872:c4124719-4124468 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCGTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAAGCGCAGGTGAGCAACAACCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References