178157

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/ParE-HTH
Location 5333650..5334115 Replicon chromosome
Accession NZ_CP063400
Organism Hydrogenophaga sp. SL48

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag IM738_RS25420 Protein ID WP_236963767.1
Coordinates 5333846..5334115 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag IM738_RS25415 Protein ID WP_236963766.1
Coordinates 5333650..5333862 (+) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IM738_RS25385 (IM738_25345) 5328905..5329834 + 930 WP_236963760.1 cation diffusion facilitator family transporter -
IM738_RS25390 (IM738_25350) 5329953..5330393 + 441 WP_236963761.1 D-aminoacyl-tRNA deacylase -
IM738_RS25395 (IM738_25355) 5330429..5331427 + 999 WP_236963762.1 hypothetical protein -
IM738_RS25400 (IM738_25360) 5331556..5332008 - 453 WP_236963763.1 rRNA maturation RNase YbeY -
IM738_RS25405 (IM738_25365) 5332013..5332993 - 981 WP_236963764.1 PhoH family protein -
IM738_RS25410 (IM738_25370) 5333031..5333609 + 579 WP_236963765.1 Holliday junction branch migration protein RuvA -
IM738_RS25415 (IM738_25375) 5333650..5333862 + 213 WP_236963766.1 DUF6290 family protein Antitoxin
IM738_RS25420 (IM738_25380) 5333846..5334115 + 270 WP_236963767.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IM738_RS25425 (IM738_25385) 5334240..5335391 - 1152 WP_236963768.1 carbonic anhydrase family protein -
IM738_RS25430 (IM738_25390) 5335528..5336586 + 1059 WP_236963769.1 Holliday junction branch migration DNA helicase RuvB -
IM738_RS25435 (IM738_25395) 5336618..5337577 + 960 WP_236963770.1 SPOR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Relaxosome protein TraY

(4-49)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10599.32 Da        Isoelectric Point: 10.3359

>T178157 WP_236963767.1 NZ_CP063400:5333846-5334115 [Hydrogenophaga sp. SL48]
MAWQIEFDPDALKELKKLDRPIQTRLVAFLRDRLSLLEDPRSIGEALSGARLGSYWKYRVGDWRIVCDIQDQRIVVRVLR
IGNRREVYR

Download         Length: 270 bp

>T178157 NZ_CP083869:c4151204-4150854 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GTGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTT
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 8031.19 Da        Isoelectric Point: 5.8451

>AT178157 WP_236963766.1 NZ_CP063400:5333650-5333862 [Hydrogenophaga sp. SL48]
MLAIRLTPDIEARLNRLTQETGRTKTALAREAILEHLDDLEDFYLAEARARKNRKTIPLTDVERELGLAN

Download         Length: 213 bp

>AT178157 NZ_CP083869:c4151449-4151198 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCGTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAAGCGCAGGTGAGCAACAACCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References