Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/upstrm_HI1419-dnstrm_HI1420 |
Location | 3033880..3034484 | Replicon | chromosome |
Accession | NZ_CP063400 | ||
Organism | Hydrogenophaga sp. SL48 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | IM738_RS14370 | Protein ID | WP_236961539.1 |
Coordinates | 3033880..3034182 (+) | Length | 101 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | IM738_RS14375 | Protein ID | WP_236961540.1 |
Coordinates | 3034179..3034484 (+) | Length | 102 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IM738_RS14355 (IM738_14360) | 3029553..3029774 | - | 222 | WP_236961536.1 | formate dehydrogenase | - |
IM738_RS14360 (IM738_14365) | 3030270..3031613 | + | 1344 | WP_236961537.1 | sigma-54 dependent transcriptional regulator | - |
IM738_RS14365 (IM738_14370) | 3031729..3033813 | + | 2085 | WP_236961538.1 | cache domain-containing protein | - |
IM738_RS14370 (IM738_14375) | 3033880..3034182 | + | 303 | WP_236961539.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
IM738_RS14375 (IM738_14380) | 3034179..3034484 | + | 306 | WP_236961540.1 | putative addiction module antidote protein | Antitoxin |
IM738_RS14380 (IM738_14385) | 3034536..3035051 | + | 516 | WP_236961541.1 | hypothetical protein | - |
IM738_RS14385 (IM738_14390) | 3035077..3035694 | - | 618 | WP_236961542.1 | molecular chaperone TorD family protein | - |
IM738_RS14390 (IM738_14395) | 3035723..3037804 | - | 2082 | WP_236966322.1 | 4Fe-4S binding protein | - |
IM738_RS14395 (IM738_14400) | 3037764..3038405 | - | 642 | WP_236961543.1 | DUF3306 domain-containing protein | - |
IM738_RS14400 (IM738_14405) | 3038467..3039267 | - | 801 | WP_236961550.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11294.06 Da Isoelectric Point: 9.6539
>T178156 WP_236961539.1 NZ_CP063400:3033880-3034182 [Hydrogenophaga sp. SL48]
VFTVLQTEDFRDWLDALKDMKAQVRIAARLRLAEAGSLGDWKSVGDGLSEMRVDVGPGYRLYFTRRQNILIVMLAGGDKS
TQAKDIKRAQKLLTQLELEP
VFTVLQTEDFRDWLDALKDMKAQVRIAARLRLAEAGSLGDWKSVGDGLSEMRVDVGPGYRLYFTRRQNILIVMLAGGDKS
TQAKDIKRAQKLLTQLELEP
Download Length: 303 bp
>T178156 NZ_CP083869:c4040710-4040423 [Escherichia coli]
ATGCCAATGGAGTTTGAATGGGATGAAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTGAAGATGCGGT
GTTATTGTTTGATGATCCACAACATTTGTCACAGCAAGAACGCATAGAAAACGGTGAGTATCGCTGGCAGACAATCGGCC
TGGTTTACGGCATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAATCGCTATGAGCATGGTTAA
ATGCCAATGGAGTTTGAATGGGATGAAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTGAAGATGCGGT
GTTATTGTTTGATGATCCACAACATTTGTCACAGCAAGAACGCATAGAAAACGGTGAGTATCGCTGGCAGACAATCGGCC
TGGTTTACGGCATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAATCGCTATGAGCATGGTTAA
Antitoxin
Download Length: 102 a.a. Molecular weight: 10752.56 Da Isoelectric Point: 10.1735
>AT178156 WP_236961540.1 NZ_CP063400:3034179-3034484 [Hydrogenophaga sp. SL48]
MSTTKMKSKLVPFDAARYLSDDTAIAEYMNAVLETGDTDLLLLALGDVARARGMAQVAKDAGLGRESLYKALTPGAKPRF
DTVVKVARALGVRLGVRPVSV
MSTTKMKSKLVPFDAARYLSDDTAIAEYMNAVLETGDTDLLLLALGDVARARGMAQVAKDAGLGRESLYKALTPGAKPRF
DTVVKVARALGVRLGVRPVSV
Download Length: 306 bp
>AT178156 NZ_CP083869:c4040436-4040134 [Escherichia coli]
ATGAGCATGGTTAAACATAAACGAGGGACCTCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGCGCTGACGAA
TAAATCCGACGAAGATATTGATTACAGTGATATCCCACCTTCCAGCGATGAGCAATGGTCTAACGCCGAACGCGGTAAGT
TTTATCGGCCATTGAAAACTCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGTTGAAGCGACCAGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA
ATGAGCATGGTTAAACATAAACGAGGGACCTCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGCGCTGACGAA
TAAATCCGACGAAGATATTGATTACAGTGATATCCCACCTTCCAGCGATGAGCAATGGTCTAACGCCGAACGCGGTAAGT
TTTATCGGCCATTGAAAACTCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGTTGAAGCGACCAGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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