Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 2356763..2357268 Replicon chromosome
Accession NZ_CP063397
Organism Rhizobium sp. SL42

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IM739_RS11190 Protein ID WP_237367847.1
Coordinates 2356763..2357017 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag IM739_RS11195 Protein ID WP_113141125.1
Coordinates 2357014..2357268 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IM739_RS11170 (IM739_11150) 2352304..2353215 + 912 WP_237367843.1 DUF4344 domain-containing metallopeptidase -
IM739_RS11175 (IM739_11155) 2353263..2354696 - 1434 WP_237367844.1 3-mercaptopyruvate sulfurtransferase -
IM739_RS11180 (IM739_11160) 2354718..2355455 - 738 WP_237367845.1 alanyl-tRNA editing protein -
IM739_RS11185 (IM739_11165) 2355464..2356501 - 1038 WP_237367846.1 cysteine synthase A -
IM739_RS11190 (IM739_11170) 2356763..2357017 - 255 WP_237367847.1 Txe/YoeB family addiction module toxin Toxin
IM739_RS11195 (IM739_11175) 2357014..2357268 - 255 WP_113141125.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IM739_RS11200 (IM739_11180) 2357480..2358160 + 681 WP_237367848.1 hypothetical protein -
IM739_RS11205 (IM739_11185) 2358176..2359618 - 1443 WP_237367849.1 deoxyribodipyrimidine photo-lyase -
IM739_RS11210 (IM739_11190) 2359718..2359945 - 228 WP_007606528.1 hypothetical protein -
IM739_RS11220 (IM739_11200) 2360371..2360652 + 282 WP_237367850.1 hypothetical protein -
IM739_RS11225 (IM739_11205) 2360912..2361175 + 264 WP_237367851.1 hypothetical protein -
IM739_RS11235 (IM739_11215) 2361562..2361891 + 330 WP_237367852.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10185.60 Da        Isoelectric Point: 9.9434

>T178150 WP_237367847.1 NZ_CP063397:c2357017-2356763 [Rhizobium sp. SL42]
VKIIFHARAWEDYLYWQSTDQKMLARVNHLIRETSRSPFQGIGKPEPLRGDLRGWWSRRIDQEHRLVYRPTEDGVLIAQC
RHHY

Download         Length: 255 bp

>T178150 NZ_CP083869:c2403507-2403331 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATAGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9520.67 Da        Isoelectric Point: 4.7037

>AT178150 WP_113141125.1 NZ_CP063397:c2357268-2357014 [Rhizobium sp. SL42]
MRTTSYSDLRKNLASLLDSVTEDRTPVLITRDRGKPAAVLMSVEDFASYEETQHLLKSPRNAERLLEAVRELDEGKGDVR
ELSE

Download         Length: 255 bp

>AT178150 NZ_CP083869:c2403285-2402869 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
CCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCTTTACCTTCGCCATTAAATAGTCACGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAGGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCATCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References