Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4307644..4308169 Replicon chromosome
Accession NZ_CP063380
Organism Pectobacterium versatile strain ECC15

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IMY97_RS19615 Protein ID WP_039539560.1
Coordinates 4307885..4308169 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID C6D956
Locus tag IMY97_RS19610 Protein ID WP_005973616.1
Coordinates 4307644..4307895 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IMY97_RS19565 (IMY97_19740) 4303447..4303782 + 336 WP_039355545.1 outer membrane protein assembly factor BamE -
IMY97_RS19570 (IMY97_19745) 4304021..4304311 - 291 WP_039470935.1 RnfH family protein -
IMY97_RS19575 (IMY97_19750) 4304292..4304738 - 447 WP_010282427.1 type II toxin-antitoxin system RatA family toxin -
IMY97_RS19580 (IMY97_19755) 4304894..4305376 + 483 WP_010282425.1 SsrA-binding protein SmpB -
IMY97_RS19590 (IMY97_19765) 4306050..4306379 - 330 WP_223193302.1 DUF1493 family protein -
IMY97_RS19595 (IMY97_19770) 4306379..4306850 - 472 Protein_3846 hypothetical protein -
IMY97_RS19600 (IMY97_19775) 4306980..4307231 + 252 WP_105879157.1 prevent-host-death protein -
IMY97_RS19605 (IMY97_23390) 4307221..4307472 + 252 WP_223193489.1 hypothetical protein -
IMY97_RS19610 (IMY97_19785) 4307644..4307895 + 252 WP_005973616.1 prevent-host-death protein Antitoxin
IMY97_RS19615 (IMY97_19790) 4307885..4308169 + 285 WP_039539560.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IMY97_RS19620 (IMY97_19795) 4308435..4308611 + 177 WP_158256803.1 hypothetical protein -
IMY97_RS19625 (IMY97_19800) 4308828..4309406 + 579 WP_107332342.1 hypothetical protein -
IMY97_RS19630 (IMY97_19805) 4309775..4310555 + 781 Protein_3853 transporter substrate-binding domain-containing protein -
IMY97_RS19635 (IMY97_19810) 4310811..4311437 + 627 WP_103861356.1 LysE family transporter -
IMY97_RS19640 (IMY97_19815) 4311483..4311965 - 483 WP_029367525.1 GNAT family N-acetyltransferase -
IMY97_RS19645 (IMY97_19820) 4312215..4312640 - 426 WP_105879155.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11034.00 Da        Isoelectric Point: 10.1716

>T178071 WP_039539560.1 NZ_CP063380:4307885-4308169 [Pectobacterium versatile]
MSYKLEFEEHALKEFKKLGAPVREQFTKKLKEVLQHPHVPANRLHGMADCYKIKLRSAGYRLVYQVLEHEIVVLVLAVGK
RERSEVYKTAKDRL

Download         Length: 285 bp

>T178071 NZ_CP083834:c2832691-2832588 [Enterobacter asburiae]
GGCAAGGCTACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9079.35 Da        Isoelectric Point: 5.0807

>AT178071 WP_005973616.1 NZ_CP063380:4307644-4307895 [Pectobacterium versatile]
MSVQPILANAAVSISDFKKSPNAALKEANGEPVAVLTNGRISGYYVSPETWEALADYQEDIELAKIARSRMKGKRVKVDL
DEL

Download         Length: 252 bp

>AT178071 NZ_CP083834:2832582-2832726 [Enterobacter asburiae]
ACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTAGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0G4JQP6

References