Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 4130187..4130713 Replicon chromosome
Accession NZ_CP063380
Organism Pectobacterium versatile strain ECC15

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag IMY97_RS18845 Protein ID WP_103861230.1
Coordinates 4130408..4130713 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag IMY97_RS18840 Protein ID WP_103861229.1
Coordinates 4130187..4130405 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IMY97_RS18820 (IMY97_18995) 4125391..4125789 - 399 WP_102118353.1 hypothetical protein -
IMY97_RS18825 (IMY97_19000) 4125786..4128665 - 2880 WP_188246996.1 conjugative transfer ATPase -
IMY97_RS18830 (IMY97_19010) 4128676..4129716 - 1041 WP_242934994.1 PilN family type IVB pilus formation outer membrane protein -
IMY97_RS18835 (IMY97_23350) 4129766..4130128 + 363 Protein_3694 molybdopterin-guanine dinucleotide biosynthesis protein MobC -
IMY97_RS18840 (IMY97_19015) 4130187..4130405 + 219 WP_103861229.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
IMY97_RS18845 (IMY97_19020) 4130408..4130713 + 306 WP_103861230.1 type II toxin-antitoxin system toxin CcdB Toxin
IMY97_RS18850 (IMY97_19025) 4130840..4132099 - 1260 WP_105879201.1 GIY-YIG nuclease family protein -
IMY97_RS18855 (IMY97_19030) 4132101..4134110 - 2010 WP_170309991.1 helicase-related protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11725.54 Da        Isoelectric Point: 4.5228

>T178068 WP_103861230.1 NZ_CP063380:4130408-4130713 [Pectobacterium versatile]
MQFIVYQYKRASHYTMFVDVQSDIVETPKRRMVIPLIESHHLSEKVDKTLFPRICIDGEDYRLMTTELSSVPVEVIGEVI
ADLGDYADEIKDAINLMFWGI

Download         Length: 306 bp

>T178068 NZ_CP083834:573404-573724 [Enterobacter asburiae]
ATGCAAATTTCAACTGTACCGGCCACGGTGCCGGTTTCGTCACGCCAGTCGCCCATACAGGTGTGGCAGCAACTGTTAAC
GTATCTGCTGGAACACCATTACGGTCTGACTCTCAACGACACACCATTTCATGACGACGCGGCCATTGAGGAGCATATCG
ACGCGGGAATAACGCTTGCCGATGCTGTTAATTTCCTGGTGGAACGTTATGAACTGGTACGCATCGACCGTAAAGGATTC
ACCAGGCAGGAGCAGACGCCATTTCTGACCGCGACTGATATTCTCAGAGCCAGGCGAGCTACCGGATTAATAAATACCTG
A

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8242.30 Da        Isoelectric Point: 9.8124

>AT178068 WP_103861229.1 NZ_CP063380:4130187-4130405 [Pectobacterium versatile]
MKHRVSVTVDKDNYQILSAAGVNISGLVNDVIGKEARRIKAEEWKKKNREGMEEVARFIAQHGSFADENRNW

Download         Length: 219 bp

>AT178068 NZ_CP083834:573049-573372 [Enterobacter asburiae]
ATGCAAAATTCATGGGGACTGAAGCGCGACATCTCGCCGTGCTTCGGTGCAAGGCTTGTGCAGGAAGGCTGTCGCCTGCA
TTTTCTGGCAGACCGTGCAGGTATTAGCGGTGCGTTTAACGAGGAGGAGGCGCTACGTCTGGATCAGGCATTTCCGCTAG
TGATGAAACAGCTTGAATTGATGCTGACAACCGGTGAACTGAATCCGCGCCATCAGCATTGCGTCACGTTGCATCATAAC
GGACTCACCTGCGAGGCGGATACTCTCGGTTCTCATGGCTATGTTTACATCGCTATTTATCCTCATACACCTGCTAGCCA
ATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References