Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) sdenTA/AbiEii(toxin)
Location 435847..437287 Replicon chromosome
Accession NZ_CP063380
Organism Pectobacterium versatile strain ECC15

Toxin (Protein)


Gene name sdenT Uniprot ID -
Locus tag IMY97_RS02000 Protein ID WP_180790295.1
Coordinates 436400..437287 (+) Length 296 a.a.

Antitoxin (Protein)


Gene name sdenA Uniprot ID -
Locus tag IMY97_RS01995 Protein ID WP_103862785.1
Coordinates 435847..436371 (+) Length 175 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IMY97_RS01965 (IMY97_01930) 430963..431520 - 558 WP_105880054.1 hypothetical protein -
IMY97_RS01970 (IMY97_22455) 431875..432111 - 237 WP_242934919.1 hypothetical protein -
IMY97_RS01975 (IMY97_22460) 432146..432586 - 441 WP_198673503.1 class I SAM-dependent methyltransferase -
IMY97_RS01980 (IMY97_01940) 432927..433319 - 393 WP_242934920.1 type II toxin-antitoxin system death-on-curing family toxin -
IMY97_RS01985 (IMY97_01945) 433316..433537 - 222 WP_010300679.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
IMY97_RS01990 (IMY97_01950) 433778..434989 - 1212 Protein_389 IS3 family transposase -
IMY97_RS01995 (IMY97_01955) 435847..436371 + 525 WP_103862785.1 hypothetical protein Antitoxin
IMY97_RS02000 (IMY97_01960) 436400..437287 + 888 WP_180790295.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
IMY97_RS02005 (IMY97_01965) 437393..438256 - 864 WP_095993164.1 YicC/YloC family endoribonuclease -
IMY97_RS02010 (IMY97_01970) 438355..439263 - 909 WP_039542502.1 LysR family transcriptional regulator -
IMY97_RS02015 (IMY97_01975) 439593..440540 - 948 WP_116586292.1 isoaspartyl peptidase/L-asparaginase -
IMY97_RS02020 (IMY97_01980) 440601..441422 - 822 WP_039296402.1 M55 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - rfaD 337966..510621 172655


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(39-265)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 296 a.a.        Molecular weight: 33993.85 Da        Isoelectric Point: 5.4564

>T178064 WP_180790295.1 NZ_CP063380:436400-437287 [Pectobacterium versatile]
MLKQQIRQIVQSTPDYAAVTPVIEKEILHHDIIDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFQPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKISIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYNIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWIKQRGIDLSKTLVEKKLTARQKQTEDFRQALSIQLANLMSEDE
VRDDFNMEMSRFIPKQIKERTLDNPEYWAYVQGEVHAIASELLNDGTPKNPFDMG

Download         Length: 888 bp

>T178064 NZ_CP083832:c118145-117660 [Enterobacter asburiae]
GTGGGACGTGTAACAGCACCAGAACCATTATCCAGCTCCCATCAACTAGCAGAGTTCGTCAGTGGTGAGGCAGTACTTGA
TGACTGGCTTAAACAGAGGGGATTAAAAAACCAAGCTCTTGGTGCAGCACGAACGTTCGTCGTTTGTAAAAGAGACACTA
AACAGGTTGTCGGTTTTTACTCTCTGGCCACCGGCAGCGTTAACCACGTGGAAGCAATGGGAAGCCTCAGGCGCAATATG
CCAGATCCAATTCCCGTAATCATACTTGCTCGCCTGGCAGTTGATGTTTCATACCGTGGCCAAGGGCTCGGGGCCGATTT
ACTGCATGATGCAGTTCTGCGCTGTTACCGTGTAGCTGAGAATATTGGAGTCCGTGCGATTATGGTTCATGCACTGACTG
AAGAAGCCAAAAACTTTTATCTTCACCATGGCTTTAAGGCATCACAAACTCAGGAACGGACATTGTTTTTAAAGTTACCA
CAGTGA

Antitoxin


Download         Length: 175 a.a.        Molecular weight: 19325.45 Da        Isoelectric Point: 9.0504

>AT178064 WP_103862785.1 NZ_CP063380:435847-436371 [Pectobacterium versatile]
MAKSDELLSALAKSVNAGGGIHSVAELAFMQGVPCDSAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIEFTHTKKPVEQIAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES

Download         Length: 525 bp

>AT178064 NZ_CP083832:c118399-118133 [Enterobacter asburiae]
ATGAAATCAGATGTTCAGCTCAACCTTAGAGCTAAAGAATCTCAAAGAGCACTTATTGATGCTGCAGCAGAGATTCTCCA
TAAATCACGCACGGACTTCATCCTGGAAATGGCATGTCAGGCTGCGGAGAATGTGATCCTCGATCGTCGCGTATTTAATT
TTAACGATGAGCAGTATGCAGAGTTTATCGATATGCTCGATGCACCGGTTTCGGATGAGGCGGCTATTGATAAACTTCTG
GCAAGGAAACCTCAGTGGGACGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References