Detailed information of TA system TA178061

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 360254..360789
• Replicon: chromosome
• Accession: NZ_CP063380
• Organism: Pectobacterium versatile strain ECC15

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: IMY97_RS01630
• Protein ID: WP_116186077.1
• Coordinates: 360254..360541 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Q6DB37
• Locus tag: IMY97_RS01635
• Protein ID: WP_010281712.1
• Coordinates: 360538..360789 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IMY97_RS01610 (IMY97_01550)	355816..357168	+	1353	WP_188246878.1	glutathione-disulfide reductase	-
IMY97_RS01615 (IMY97_22420)	357312..357668	-	357	WP_242934913.1	DUF2726 domain-containing protein	-
IMY97_RS01620 (IMY97_01560)	357688..358794	-	1107	WP_242934914.1	DEAD/DEAH box helicase	-
IMY97_RS01625 (IMY97_22425)	358855..360099	-	1245	WP_242934915.1	AAA domain-containing protein	-
IMY97_RS01630 (IMY97_01570)	360254..360541	-	288	WP_116186077.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
IMY97_RS01635 (IMY97_01575)	360538..360789	-	252	WP_010281712.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
IMY97_RS01640 (IMY97_01580)	361047..361952	+	906	WP_188246876.1	siderophore-interacting protein	-
IMY97_RS01645 (IMY97_01585)	361987..362742	-	756	WP_130623730.1	thiol:disulfide interchange protein DsbG	-
IMY97_RS01650 (IMY97_01590)	363009..363632	+	624	WP_119159034.1	LysE family translocator	-
IMY97_RS01655 (IMY97_01595)	363693..364733	-	1041	WP_188246875.1	HipA domain-containing protein	-
IMY97_RS01660 (IMY97_01600)	364730..365044	-	315	WP_103943147.1	HipA N-terminal domain-containing protein	-
IMY97_RS01665 (IMY97_01605)	365029..365355	-	327	WP_103862833.1	helix-turn-helix domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	rfaD	337966..510621	172655

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11030.10 Da
• Isoelectric Point: 10.3527

>T178061 WP_116186077.1 NZ_CP063380:c360541-360254 [Pectobacterium versatile]
MSYSVKFREDALKEWLKLDKAIQQQFAKKLKKCCENPHIPSAKLRGMKDCYKIKLRASGFRLVYEVIDDVLVIAVVAVGK
RERSGVYHLASERMR

Nucleotide

• Length: 288 bp

>T178061 NZ_CP083831:93348-94673 [Enterobacter asburiae]
ATGAGCCGGAAACAGCAGCGTCTGGCAATCTGGATGAACGGAATCAAAGTCGGATACTGGGAAAAAAGTAAAGGGGTAGA
CAGCTTACAATACCTTCCTGACTGGAGTGCAGACGAACAGGGAAGGCCGCTGTCATTGTCCCTTCCTTTTACTCCCGGGA
ACCAGGTCTGGCGTGGAAATGTGGTACGTGACTATTTTGATAATTTACTCCCGGACAGCGAAGGCATACGCAGACGTCTG
GCAATGCGTTACAAGGCCGATAGCCTGGAGCCTTTTGATCTTCTGACGGAGCTGGGAAAAGACTGCGTGGGCGCGATACA
GCTGCTTCATGACGGAGATGAACCCACAGATTTATATTCCGTGAAGTATCACCCGCTTACTGAATCAGAAATTGCGGCAA
CTTTGCGTAATACCACGGAGACATTGCTACCGGGCAGGCCAGAAGATAACGACGACTTACGTTTATCTATTGCCGGTGCT
CAGGAGAAAACAGCCCTACTGTGGCATGAAGATCGGTGGTGTATGCCGGAGGGTAATACACCAACGACGCATATATTCAA
GCTACCGCTCGGACTTGTGGGGAACATGAAAGCCGACATGCGCTCGTCGGTTGAAAATGAATGGCTCTGCTCGGTACTTC
TCGAACAGTACGGGCTCCCCGTGGCAAGAACGCAGATTGCTCACTTTGAAGATCAGAAAGCGCTGGTGGTAGAACGTTTT
GACCGAAAATGGTCAGGAAACGGACAATGGATCATTCGTTTACCCCAGGAGGATATGTGTCAGGCCCTGGGCATTTCGCC
ATTACGAAAATATCAGGCGGACGGCGGGCCAGGTATATCGGAAATTATGGAAGTTCTGAGTAATTCAGACCGTGCTGAGC
GTGACAAAGCGCAGTTTTTTATGACGCAGATAGTTTTCTGGATGATGGCCGCAACAGATGGCCACGCTAAAAATTTCAGT
ATTTCTATTGGGCCACAGGGACGTTATCACCTTACACCACTCTATGATGTGTTGTCGGCATGGCCGGTGATCGGTCATGG
GAACAATCAGATATCCTGGCAGAAGTGCAAACTGGCGATGGCCGTACGTGGCAGTAGCAACTATTACCAGATATATCGAA
TACAACGACGCCACTGGATCAGGCATGGTGAGATAACCGGCCTGAGTAAACAGCAGACAGAGGCGATGATAGAGGAAATC
ATCGCCAGAACCCCGGGTGTCATTGAACGTGTTAGCGGGCTTCTTCCGGACCAGTTCCCCCAGCAGCTTGCGGAAAGTAT
TTTTGATGGAATGAGGCAGCAATGCAGGCGCCTGGCTGAGAAATGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9117.47 Da
• Isoelectric Point: 4.0637

>AT178061 WP_010281712.1 NZ_CP063380:c360789-360538 [Pectobacterium versatile]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Nucleotide

• Length: 252 bp

>AT178061 NZ_CP083831:93050-93343 [Enterobacter asburiae]
ATCAATAATGATTACCCGTTAAACACGCTCAACCAGTTGCGTCCCTTGCTCATTGGTTTTCGCAAGGCGAATGGCCTGAC
GCAAAAAGACCTGTCCGAAAGGTTAGGGGTCACTCAACAGACATACTCACGTCTGGAAGCCAACCCTGCCAGTGCGAGCA
TTGAACGGCTATTCAAGGTGTTTTCTATCCTGGGCGTAAAAATCAGCTTCTCCTCGACAACCGCCTCTTCAGAGGGGAAG
CAGACGGAAGAAATGCTTAAATCAAACTCACCTGCACGACAGGAGAAATGGTAA

Structures

Antitoxin

• AlphaFold DB: A0A0M2EZP0