Detailed information of TA system TA178015

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 1120542..1121116
• Replicon: chromosome
• Accession: NZ_CP063362
• Organism: Xanthobacter sp. YN2

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: EZH22_RS05350
• Protein ID: WP_203194715.1
• Coordinates: 1120542..1120850 (-)
• Length: 103 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: EZH22_RS05355
• Protein ID: WP_203194716.1
• Coordinates: 1120838..1121116 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EZH22_RS05345	1115891..1118275	-	2385	WP_203194714.1	hypothetical protein	-
EZH22_RS05350	1120542..1120850	-	309	WP_203194715.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EZH22_RS05355	1120838..1121116	-	279	WP_203194716.1	CopG family ribbon-helix-helix protein	Antitoxin
EZH22_RS05360	1121920..1122816	+	897	WP_203194717.1	thermonuclease family protein	-
EZH22_RS05365	1123044..1124387	+	1344	WP_203196393.1	M48 family metalloprotease	-
EZH22_RS05370	1124480..1124935	+	456	WP_203194718.1	universal stress protein	-
EZH22_RS05375	1125006..1125707	+	702	WP_203194719.1	GntR family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-93)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 103 a.a.
• Molecular weight: 11293.83 Da
• Isoelectric Point: 8.6745

>T178015 WP_203194715.1 NZ_CP063362:c1120850-1120542 [Xanthobacter sp. YN2]
MPQVRFSPAAIRDLEGLRSFLSPKNPAAAKRAGEAIIDGVRALGSHPHMGRTIDGLPEQFRDWLIPFGDSGYVARYHFGD
DGVTILLLRHQREMDWSGKGHG

Nucleotide

• Length: 309 bp

>T178015 NZ_CP083815:c251473-251186 [Enterobacter asburiae]
ATGCATAAATTAACACCCTACGATCCAGCCAATGCGCTGGTGGATGACGAGGAAATCGCCGTGTTTATGGCTGATGCCTT
AGAAACGGGCGATTCAGCGTATATTGCTAAAGCTCTGGGCGTCATCGCGCGAGCGAAAGGAATGTCGACCATTTCACAGC
AAACTGGCCTATCACGAGAGCAACTGTATCGATCGTTCAGTGATAAAGGAAACCCAACGCTTAAAACCACTCTGGCGGTC
ATGAAAGCATTGGGTCTTGGGCTAACAATCAAACACGCTGGAGATTAA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10711.03 Da
• Isoelectric Point: 6.4734

>AT178015 WP_203194716.1 NZ_CP063362:c1121116-1120838 [Xanthobacter sp. YN2]
MATATSIKLDDELKGRIQRLAEVRRRSSHWIMREAIAQYVEREERREALRQDTVKAWDEFQATGVHATAEDVEKWLSSWG
TEGELPAPQCRK

Nucleotide

• Length: 279 bp

>AT178015 NZ_CP083815:c251778-251476 [Enterobacter asburiae]
ATGAAGGAGATCGTTCAGACAGAATCCTTCCAACGCTGGGAGCAAAACTTAAAAGATCGGCGAGCGAAAACCATTATCGC
TTCCCGCCTCTTTCGGTTGGCAAATGGTTTAGCGGGCGACATTAAACCCGTGGGCGAAGGTATAAGTGAGCTGAGGATCC
ACTATGGTCCGGGCTACAGAATCTATTTTAAAGACCAGGGCAATTGCATCATCGTGCTGTTGTGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTTATGGCAAAAATGCTGAGCAATCCCAATGGCAGGAGTGAATGA