Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-YafN |
Location | 3018024..3018549 | Replicon | chromosome |
Accession | NZ_CP063354 | ||
Organism | Serratia marcescens strain SCQ1 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | CA266_RS14270 | Protein ID | WP_015377296.1 |
Coordinates | 3018024..3018308 (-) | Length | 95 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A8B4GIN1 |
Locus tag | CA266_RS14275 | Protein ID | WP_004928423.1 |
Coordinates | 3018298..3018549 (-) | Length | 84 a.a. |
Genomic Context
Location: 3013284..3014417 (1134 bp)
Type: Others
Protein ID: WP_033640832.1
Type: Others
Protein ID: WP_033640832.1
Location: 3014442..3015404 (963 bp)
Type: Others
Protein ID: WP_016928361.1
Type: Others
Protein ID: WP_016928361.1
Location: 3015401..3016246 (846 bp)
Type: Others
Protein ID: WP_193842685.1
Type: Others
Protein ID: WP_193842685.1
Location: 3016351..3016830 (480 bp)
Type: Others
Protein ID: WP_028127974.1
Type: Others
Protein ID: WP_028127974.1
Location: 3016900..3018027 (1128 bp)
Type: Others
Protein ID: WP_151254362.1
Type: Others
Protein ID: WP_151254362.1
Location: 3018024..3018308 (285 bp)
Type: Toxin
Protein ID: WP_015377296.1
Type: Toxin
Protein ID: WP_015377296.1
Location: 3018298..3018549 (252 bp)
Type: Antitoxin
Protein ID: WP_004928423.1
Type: Antitoxin
Protein ID: WP_004928423.1
Location: 3018651..3019385 (735 bp)
Type: Others
Protein ID: WP_016928355.1
Type: Others
Protein ID: WP_016928355.1
Location: 3019586..3020254 (669 bp)
Type: Others
Protein ID: WP_033637817.1
Type: Others
Protein ID: WP_033637817.1
Location: 3020254..3020970 (717 bp)
Type: Others
Protein ID: WP_028127976.1
Type: Others
Protein ID: WP_028127976.1
Location: 3020980..3021711 (732 bp)
Type: Others
Protein ID: WP_004928409.1
Type: Others
Protein ID: WP_004928409.1
Location: 3021744..3022472 (729 bp)
Type: Others
Protein ID: WP_016928352.1
Type: Others
Protein ID: WP_016928352.1
Location: 3022736..3023278 (543 bp)
Type: Others
Protein ID: WP_028127978.1
Type: Others
Protein ID: WP_028127978.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CA266_RS14245 | 3013284..3014417 | + | 1134 | WP_033640832.1 | putrescine ABC transporter ATP-binding subunit PotG | - |
CA266_RS14250 | 3014442..3015404 | + | 963 | WP_016928361.1 | putrescine ABC transporter permease PotH | - |
CA266_RS14255 | 3015401..3016246 | + | 846 | WP_193842685.1 | putrescine ABC transporter permease PotI | - |
CA266_RS14260 | 3016351..3016830 | + | 480 | WP_028127974.1 | YbjO family protein | - |
CA266_RS14265 | 3016900..3018027 | + | 1128 | WP_151254362.1 | 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC | - |
CA266_RS14270 | 3018024..3018308 | - | 285 | WP_015377296.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
CA266_RS14275 | 3018298..3018549 | - | 252 | WP_004928423.1 | prevent-host-death protein | Antitoxin |
CA266_RS14280 | 3018651..3019385 | - | 735 | WP_016928355.1 | arginine ABC transporter substrate-binding protein | - |
CA266_RS14285 | 3019586..3020254 | - | 669 | WP_033637817.1 | arginine ABC transporter permease ArtM | - |
CA266_RS14290 | 3020254..3020970 | - | 717 | WP_028127976.1 | arginine ABC transporter permease ArtQ | - |
CA266_RS14295 | 3020980..3021711 | - | 732 | WP_004928409.1 | arginine ABC transporter substrate-binding protein | - |
CA266_RS14300 | 3021744..3022472 | - | 729 | WP_016928352.1 | arginine ABC transporter ATP-binding protein ArtP | - |
CA266_RS14305 | 3022736..3023278 | - | 543 | WP_028127978.1 | lipoprotein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 95 a.a. Molecular weight: 10803.94 Da Isoelectric Point: 10.6941
>T177998 WP_015377296.1 NZ_CP063354:c3018308-3018024 [Serratia marcescens]
MTYKLEFEEHALKEFKKLSPVIREQFKKKLASVLVNPHIPANKLAGLPDCYKIKLRASGFRLVYRVMETEIVVLVLSVGK
RERSAAYTAAKKRL
MTYKLEFEEHALKEFKKLSPVIREQFKKKLASVLVNPHIPANKLAGLPDCYKIKLRASGFRLVYRVMETEIVVLVLSVGK
RERSAAYTAAKKRL
Download Length: 285 bp
>T177998 NZ_CP083805:c1899367-1899212 [Staphylococcus argenteus]
ATGTCTAAAGATAAAGATGCAAAATTAAATTATCACGAAGAAGAAAACAGTATGGTAACTGATTTTGAAGATTTAAAAGA
ATTAGGTAAAGAGATGGAACAAATTTCAGATCAAAATGATCAAGAGAAGAGTACTGATGAAAAGAATAGCCATTAA
ATGTCTAAAGATAAAGATGCAAAATTAAATTATCACGAAGAAGAAAACAGTATGGTAACTGATTTTGAAGATTTAAAAGA
ATTAGGTAAAGAGATGGAACAAATTTCAGATCAAAATGATCAAGAGAAGAGTACTGATGAAAAGAATAGCCATTAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9108.39 Da Isoelectric Point: 4.5203
>AT177998 WP_004928423.1 NZ_CP063354:c3018549-3018298 [Serratia marcescens]
MTVQPILADSAVSISDFKKSPNAALKEAQGQPVAVLTNGKISGYYVSPETWEAIAEYLEDIELAEIVRSRMNGKRIKVNL
DDL
MTVQPILADSAVSISDFKKSPNAALKEAQGQPVAVLTNGKISGYYVSPETWEAIAEYLEDIELAEIVRSRMNGKRIKVNL
DDL
Download Length: 252 bp
>AT177998 NZ_CP083805:c1899999-1899400 [Staphylococcus argenteus]
ATGGCAATGAACTTTAAAGTATTTGACAACAGTCAACTTGTAGCAGAATATGCTGCAGATATTATTAGAAAACAATTTAA
CAATAATCCTACTACAATTGCAGGTTTTCATTTGGATACAGACCAAGCACCAGTATTAGATGAACTAAAGAAAAATGTTG
AGAAACACGCTGTTGATTTTAGTCAAATAAATATTTTAGATTATGACAATAAAAAATCTTATTTTGAAGCATTAGGCGTG
CCAGCAAGTCAAATCTATCCAATTGCGTTTGAAAAAGATGCTATTGAATTTATCTCTGACAAAATTAAAACTAAAGAAAA
TAAAGGCAAACTAACATTACAAGTTGTTTCTATTGATGAGCATGGAAAATTAAATGTTAGTATCCGCCAAGGTTTAATGG
AAGCGAGAGAAATATTTTTAGTTGTGACAGGTGCTAATAAAAAGGAAGTTGTTGAAAAATTATACCAAGAAAATGGTAAA
ACAAGTTTCGAACCATCTGACTTAAAATCACATAGAATGGTAAATGTTATTCTTGATAAAGAAGCGGCTGCAGGTTTACC
TGAAGATGTCAAAGCTTACTTTACATCTCGCTTTGCTTAA
ATGGCAATGAACTTTAAAGTATTTGACAACAGTCAACTTGTAGCAGAATATGCTGCAGATATTATTAGAAAACAATTTAA
CAATAATCCTACTACAATTGCAGGTTTTCATTTGGATACAGACCAAGCACCAGTATTAGATGAACTAAAGAAAAATGTTG
AGAAACACGCTGTTGATTTTAGTCAAATAAATATTTTAGATTATGACAATAAAAAATCTTATTTTGAAGCATTAGGCGTG
CCAGCAAGTCAAATCTATCCAATTGCGTTTGAAAAAGATGCTATTGAATTTATCTCTGACAAAATTAAAACTAAAGAAAA
TAAAGGCAAACTAACATTACAAGTTGTTTCTATTGATGAGCATGGAAAATTAAATGTTAGTATCCGCCAAGGTTTAATGG
AAGCGAGAGAAATATTTTTAGTTGTGACAGGTGCTAATAAAAAGGAAGTTGTTGAAAAATTATACCAAGAAAATGGTAAA
ACAAGTTTCGAACCATCTGACTTAAAATCACATAGAATGGTAAATGTTATTCTTGATAAAGAAGCGGCTGCAGGTTTACC
TGAAGATGTCAAAGCTTACTTTACATCTCGCTTTGCTTAA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
No matching records found |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A8B4GIN1 |