Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3018024..3018549 Replicon chromosome
Accession NZ_CP063354
Organism Serratia marcescens strain SCQ1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CA266_RS14270 Protein ID WP_015377296.1
Coordinates 3018024..3018308 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8B4GIN1
Locus tag CA266_RS14275 Protein ID WP_004928423.1
Coordinates 3018298..3018549 (-) Length 84 a.a.

Genomic Context


CA266_RS14245CA266_RS14250CA266_RS14255CA266_RS14260CA266_RS14265CA266_RS14270CA266_RS14275CA266_RS14280CA266_RS14285CA266_RS14290CA266_RS14295CA266_RS14300CA266_RS14305
Location: 3013284..3014417 (1134 bp)
Type: Others
Protein ID: WP_033640832.1
Location: 3014442..3015404 (963 bp)
Type: Others
Protein ID: WP_016928361.1
Location: 3015401..3016246 (846 bp)
Type: Others
Protein ID: WP_193842685.1
Location: 3016351..3016830 (480 bp)
Type: Others
Protein ID: WP_028127974.1
Location: 3016900..3018027 (1128 bp)
Type: Others
Protein ID: WP_151254362.1
Location: 3018024..3018308 (285 bp)
Type: Toxin
Protein ID: WP_015377296.1
Location: 3018298..3018549 (252 bp)
Type: Antitoxin
Protein ID: WP_004928423.1
Location: 3018651..3019385 (735 bp)
Type: Others
Protein ID: WP_016928355.1
Location: 3019586..3020254 (669 bp)
Type: Others
Protein ID: WP_033637817.1
Location: 3020254..3020970 (717 bp)
Type: Others
Protein ID: WP_028127976.1
Location: 3020980..3021711 (732 bp)
Type: Others
Protein ID: WP_004928409.1
Location: 3021744..3022472 (729 bp)
Type: Others
Protein ID: WP_016928352.1
Location: 3022736..3023278 (543 bp)
Type: Others
Protein ID: WP_028127978.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CA266_RS142453013284..3014417+1134WP_033640832.1putrescine ABC transporter ATP-binding subunit PotG-
CA266_RS142503014442..3015404+963WP_016928361.1putrescine ABC transporter permease PotH-
CA266_RS142553015401..3016246+846WP_193842685.1putrescine ABC transporter permease PotI-
CA266_RS142603016351..3016830+480WP_028127974.1YbjO family protein-
CA266_RS142653016900..3018027+1128WP_151254362.123S rRNA (uracil(747)-C(5))-methyltransferase RlmC-
CA266_RS142703018024..3018308-285WP_015377296.1type II toxin-antitoxin system RelE/ParE family toxinToxin
CA266_RS142753018298..3018549-252WP_004928423.1prevent-host-death proteinAntitoxin
CA266_RS142803018651..3019385-735WP_016928355.1arginine ABC transporter substrate-binding protein-
CA266_RS142853019586..3020254-669WP_033637817.1arginine ABC transporter permease ArtM-
CA266_RS142903020254..3020970-717WP_028127976.1arginine ABC transporter permease ArtQ-
CA266_RS142953020980..3021711-732WP_004928409.1arginine ABC transporter substrate-binding protein-
CA266_RS143003021744..3022472-729WP_016928352.1arginine ABC transporter ATP-binding protein ArtP-
CA266_RS143053022736..3023278-543WP_028127978.1lipoprotein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-83)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 95 a.a.        Molecular weight: 10803.94 Da        Isoelectric Point: 10.6941

>T177998 WP_015377296.1 NZ_CP063354:c3018308-3018024 [Serratia marcescens]
MTYKLEFEEHALKEFKKLSPVIREQFKKKLASVLVNPHIPANKLAGLPDCYKIKLRASGFRLVYRVMETEIVVLVLSVGK
RERSAAYTAAKKRL

Download         Length: 285 bp

>T177998 NZ_CP083805:c1899367-1899212 [Staphylococcus argenteus]
ATGTCTAAAGATAAAGATGCAAAATTAAATTATCACGAAGAAGAAAACAGTATGGTAACTGATTTTGAAGATTTAAAAGA
ATTAGGTAAAGAGATGGAACAAATTTCAGATCAAAATGATCAAGAGAAGAGTACTGATGAAAAGAATAGCCATTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9108.39 Da        Isoelectric Point: 4.5203

>AT177998 WP_004928423.1 NZ_CP063354:c3018549-3018298 [Serratia marcescens]
MTVQPILADSAVSISDFKKSPNAALKEAQGQPVAVLTNGKISGYYVSPETWEAIAEYLEDIELAEIVRSRMNGKRIKVNL
DDL

Download         Length: 252 bp

>AT177998 NZ_CP083805:c1899999-1899400 [Staphylococcus argenteus]
ATGGCAATGAACTTTAAAGTATTTGACAACAGTCAACTTGTAGCAGAATATGCTGCAGATATTATTAGAAAACAATTTAA
CAATAATCCTACTACAATTGCAGGTTTTCATTTGGATACAGACCAAGCACCAGTATTAGATGAACTAAAGAAAAATGTTG
AGAAACACGCTGTTGATTTTAGTCAAATAAATATTTTAGATTATGACAATAAAAAATCTTATTTTGAAGCATTAGGCGTG
CCAGCAAGTCAAATCTATCCAATTGCGTTTGAAAAAGATGCTATTGAATTTATCTCTGACAAAATTAAAACTAAAGAAAA
TAAAGGCAAACTAACATTACAAGTTGTTTCTATTGATGAGCATGGAAAATTAAATGTTAGTATCCGCCAAGGTTTAATGG
AAGCGAGAGAAATATTTTTAGTTGTGACAGGTGCTAATAAAAAGGAAGTTGTTGAAAAATTATACCAAGAAAATGGTAAA
ACAAGTTTCGAACCATCTGACTTAAAATCACATAGAATGGTAAATGTTATTCTTGATAAAGAAGCGGCTGCAGGTTTACC
TGAAGATGTCAAAGCTTACTTTACATCTCGCTTTGCTTAA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A8B4GIN1

References