Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 1003354..1003946 Replicon chromosome
Accession NZ_CP063354
Organism Serratia marcescens strain SCQ1

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag CA266_RS04810 Protein ID WP_049300714.1
Coordinates 1003596..1003946 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag CA266_RS04805 Protein ID WP_049300713.1
Coordinates 1003354..1003602 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CA266_RS04785 999174..999512 + 339 WP_016930352.1 PTS lactose/cellobiose transporter subunit IIA -
CA266_RS04790 999509..1000816 + 1308 WP_151254276.1 6-phospho-beta-glucosidase -
CA266_RS04795 1000887..1001867 + 981 WP_016930354.1 LacI family transcriptional regulator -
CA266_RS04800 1002059..1003243 + 1185 WP_004930336.1 MFS transporter TsgA -
CA266_RS04805 1003354..1003602 + 249 WP_049300713.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
CA266_RS04810 1003596..1003946 + 351 WP_049300714.1 type II toxin-antitoxin system ChpB family toxin Toxin
CA266_RS04815 1003943..1005226 - 1284 WP_060441380.1 cytosine deaminase -
CA266_RS04820 1005515..1008064 + 2550 WP_117287518.1 nitrite reductase large subunit NirB -
CA266_RS04825 1008061..1008387 + 327 WP_115436596.1 nitrite reductase small subunit NirD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

Antitoxin PemI-like

(1-82)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12404.41 Da        Isoelectric Point: 11.5657

>T177995 WP_049300714.1 NZ_CP063354:1003596-1003946 [Serratia marcescens]
MVKRPVFQRGDLIRVSLNPVVGREQQGDFRPALVLSPREFNALGMVLVAPISQGANFARTAGFTVSLSGSGTATQGVILI
NQVRMMDLAGRSAQFIERAPGEVIADALARLQAIID

Download         Length: 351 bp

>T177995 NZ_CP083804:c3329613-3329272 [Xanthomonas translucens pv. pistacia]
ATGGTAGATCCCCAGTGGGTTCCTCGTCGGTCTGAAATAATTCATCTGGATGATATTGGTGGGGCCGGTCATGAGCAGCA
TGGTGACCGGCCTCACTTGGTTCTTACTGCGAAGGGATACAACGACAAGACAAGTCTTGTCGTTTGTGTTCCTGTCACAA
CTAAAACCAAAGGTAATCCTTTCGAAGTGGGTTTGAAGGGCCTGAATAATCCAAGTTTCGCACTGGCAAATCAGGTCATA
ACAGCGGACTGGCGTGCACGGAGAGCTTTTGCACGAGGGATCGCTAGCAAGGCCGAAATGCTTGAAGTCGATGCCAAGGT
TCGTGCGTTACTTCAACTTTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9069.53 Da        Isoelectric Point: 4.5026

>AT177995 WP_049300713.1 NZ_CP063354:1003354-1003602 [Serratia marcescens]
MKVFIKKWGNSAGMLVPSALMNELELQVGQEMDMQVIDGALVIKPVKKRYSLQQLLDGCDGEAPAAADDNWEHMPPAGKE
VW

Download         Length: 249 bp

>AT177995 NZ_CP083804:c3329849-3329607 [Xanthomonas translucens pv. pistacia]
ATGGCTGTTTTGAAGATGTGGGGAAATAGTGCTGCGGTGCGGATTCCAGCGACTTATCTTGAGGAGTCAAAGTTTTCCAT
TGATGAGCCTCTTGTAATCACAGCCGAGGAAGGACGTATTGTGATCGAATCAAGCAAGCCTTCTTATGATCTTGCTGACT
TGGTTGCCCAAATCACTCCCGAAAACACGCACGGTTTTGCTGCTCATGCTCAAAAAGTTGGAGCGGAGGATATTGAATGG
TAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References