Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 438451..439120 Replicon chromosome
Accession NZ_CP063354
Organism Serratia marcescens strain SCQ1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag CA266_RS02065 Protein ID WP_016929976.1
Coordinates 438451..438873 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8G2G4M4
Locus tag CA266_RS02070 Protein ID WP_004931679.1
Coordinates 438854..439120 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CA266_RS02045 434337..434855 + 519 WP_004931683.1 flavodoxin FldB -
CA266_RS02050 434893..436257 - 1365 WP_193843065.1 cell envelope integrity protein CreD -
CA266_RS02055 436338..437756 - 1419 WP_016929974.1 two-component system sensor histidine kinase CreC -
CA266_RS02060 437753..438451 - 699 WP_016929975.1 two-component system response regulator CreB -
CA266_RS02065 438451..438873 - 423 WP_016929976.1 protein YgfX Toxin
CA266_RS02070 438854..439120 - 267 WP_004931679.1 FAD assembly factor SdhE Antitoxin
CA266_RS02075 439441..440433 + 993 WP_049300372.1 tRNA-modifying protein YgfZ -
CA266_RS02080 440472..440969 - 498 WP_143778659.1 DUF2165 domain-containing protein -
CA266_RS02085 441120..441794 - 675 WP_028127690.1 hemolysin III family protein -
CA266_RS02090 441978..442586 + 609 WP_028127691.1 HD domain-containing protein -
CA266_RS02095 442627..443553 - 927 WP_033639466.1 ribokinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16501.62 Da        Isoelectric Point: 11.2159

>T177992 WP_016929976.1 NZ_CP063354:c438873-438451 [Serratia marcescens]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGFGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGMLLTLQPMEGKKRRRLWLASDCMSKEEWRHLRQLLLHPPAGNGEEP

Download         Length: 423 bp

>T177992 NZ_CP083804:280910-281044 [Xanthomonas translucens pv. pistacia]
ATGAAGCGTACTTTTGCGTGGATGCTGCTGGCGATGTTTTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10387.89 Da        Isoelectric Point: 4.7921

>AT177992 WP_004931679.1 NZ_CP063354:c439120-438854 [Serratia marcescens]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT177992 NZ_CP083804:280659-280811 [Xanthomonas translucens pv. pistacia]
ATGAAGCGACTGTTCACCTTGACGATGCTGACCCTGTTCTGTGCAGGCATGCTGACTGGCTGCAACACCATGGCCGGTGC
CGGCAAGGATATGCAGAAGGCCGGCGATAAGGTGGAAAACAAGGCCGACGACTGCAAAGACGGCAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References