Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 88979..89635 Replicon chromosome
Accession NZ_CP063354
Organism Serratia marcescens strain SCQ1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CA266_RS00425 Protein ID WP_021504433.1
Coordinates 88979..89368 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A8G2LCA8
Locus tag CA266_RS00430 Protein ID WP_004941563.1
Coordinates 89372..89635 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CA266_RS00410 85447..86877 + 1431 WP_193843016.1 multidrug transporter subunit MdtD -
CA266_RS00415 86874..88256 + 1383 WP_016926705.1 two-component system sensor histidine kinase BaeS -
CA266_RS00420 88256..88972 + 717 WP_004941568.1 two-component system response regulator BaeR -
CA266_RS00425 88979..89368 - 390 WP_021504433.1 type II toxin-antitoxin system VapC family toxin Toxin
CA266_RS00430 89372..89635 - 264 WP_004941563.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
CA266_RS00435 89973..90311 + 339 WP_004941561.1 YegP family protein -
CA266_RS00440 90490..91842 + 1353 WP_193843017.1 tRNA 5-hydroxyuridine modification protein YegQ -
CA266_RS00445 91899..92060 - 162 WP_162838157.1 hypothetical protein -
CA266_RS00450 92310..93215 + 906 WP_015378742.1 lipid kinase YegS -
CA266_RS00455 93384..94598 + 1215 WP_016926700.1 D-galactonate dehydratase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-119)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14398.63 Da        Isoelectric Point: 8.4983

>T177991 WP_021504433.1 NZ_CP063354:c89368-88979 [Serratia marcescens]
MYMFDTNTVSHLFRQHPQVLNVMEKLPPSAVCISSVTEAELRYGVAKRRNKALQSMVEAFLAAVTVYAWDSEAARCYGEM
RANMERKGKIMGAMDQLIAAHAQSRGATLVTNDRAFAMVPGLAVEDWTR

Download         Length: 390 bp

>T177991 NZ_CP083804:280659-280811 [Xanthomonas translucens pv. pistacia]
ATGAAGCGACTGTTCACCTTGACGATGCTGACCCTGTTCTGTGCAGGCATGCTGACTGGCTGCAACACCATGGCCGGTGC
CGGCAAGGATATGCAGAAGGCCGGCGATAAGGTGGAAAACAAGGCCGACGACTGCAAAGACGGCAAGTGCTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10062.31 Da        Isoelectric Point: 4.6702

>AT177991 WP_004941563.1 NZ_CP063354:c89635-89372 [Serratia marcescens]
MERIAKLFKNGRNQAVRLPVEFEFDTDRVYIRRDREGNVILSKYPAKPDSWAPLLSIIAQTPVPQEFLGAEDRQQGVADR
DPFSEEE

Download         Length: 264 bp

>AT177991 NZ_CP083804:280910-281044 [Xanthomonas translucens pv. pistacia]
ATGAAGCGTACTTTTGCGTGGATGCTGCTGGCGATGTTTTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References