Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 4928224..4929043 Replicon chromosome
Accession NZ_CP063301
Organism Klebsiella grimontii strain M5a1

Toxin (Protein)


Gene name yjhX Uniprot ID A0A9E1D5M6
Locus tag INR80_RS23355 Protein ID WP_004132607.1
Coordinates 4928786..4929043 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID A0A9E1DGJ5
Locus tag INR80_RS23350 Protein ID WP_004132606.1
Coordinates 4928224..4928775 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
INR80_RS23335 4923613..4925010 + 1398 WP_004132593.1 MFS transporter -
INR80_RS23340 4925134..4926474 + 1341 WP_049088521.1 carbohydrate porin -
INR80_RS23345 4926578..4928206 - 1629 WP_064371487.1 SAM-dependent methyltransferase -
INR80_RS23350 4928224..4928775 - 552 WP_004132606.1 N-acetyltransferase Antitoxin
INR80_RS23355 4928786..4929043 - 258 WP_004132607.1 YjhX family toxin Toxin
INR80_RS23360 4929627..4930811 + 1185 WP_004132609.1 mannonate dehydratase -
INR80_RS23365 4930888..4932363 + 1476 WP_004132611.1 fructuronate reductase -
INR80_RS23370 4932500..4933276 + 777 WP_004132612.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(34-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9538.04 Da        Isoelectric Point: 11.1381

>T177879 WP_004132607.1 NZ_CP063301:c4929043-4928786 [Klebsiella grimontii]
MNLSRQEQRTLHVLAKGGRIAHVRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

>T177879 NZ_CP083746:c2032436-2032254 [Pseudomonas sp. p1(2021b)]
GTGCAAAGCAGGCAGTTGATCAAGGAGCTTGAAGCCGCTGGATGGGTTCTGAAACGAGTCACCGGAAGCCACCACATCTT
CAAACACCCCAACAACCCAAACTCGATACCAGTGCCACACCCCAAGAAAGACCTACCGATCGGCACGGTAAAGAGCATCA
AGGAACGAGCCGGGTTGAAATGA

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 19990.89 Da        Isoelectric Point: 7.2343

>AT177879 WP_004132606.1 NZ_CP063301:c4928775-4928224 [Klebsiella grimontii]
MTNHSFTFHVASEGDTNDILHVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGKAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGAGVGGGLIRHGIEQLKAMGSQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEALKACWMLQPLSS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp

>AT177879 NZ_CP083746:c2032216-2031815 [Pseudomonas sp. p1(2021b)]
ATGCAATACCCAATCTGCATCGAGTGGGGCGACGAGAACACCGCCATCGGCATCCAGATCCCTGACATTCCAGGCGCCGT
GACCGCTGGAGACACGTTCGAGGAGGCCTACGCGGCAGCCGTCGAGGTTGCCCACATCATGCTGGAAGAGATCGCCGGCA
GCGGCCAGGCCATTCCCATGCCATCCAGCGCAGCGGCGCACCGTGGCAATCCCGACTTCGCGGATATGGGCTGGGGCATG
CTGGAGATCGACATAACCCCATACCTGGGCAAGACCGAGAAGGTCAATGTCACCCTGCCCGGCTTCGTCATCCAGCAGAT
CGACCGCTATGTCCGGGATCACAACGTGAAAAGCCGTTCCTCGTTCCTGGCTGATGCCGCCATGGAAAAACTGGGACGGT
AG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References