Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4733355..4733890 Replicon chromosome
Accession NZ_CP063242
Organism Pectobacterium carotovorum strain XP-13

Toxin (Protein)


Gene name relE Uniprot ID A0A837DHH7
Locus tag IHJ55_RS20990 Protein ID WP_010296545.1
Coordinates 4733603..4733890 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A837DL69
Locus tag IHJ55_RS20985 Protein ID WP_010296546.1
Coordinates 4733355..4733606 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHJ55_RS20965 4729819..4730256 + 438 WP_010296551.1 RICIN domain-containing protein -
IHJ55_RS20970 4730501..4731124 - 624 WP_039474438.1 LysE family translocator -
IHJ55_RS20975 4731403..4732158 + 756 WP_010296548.1 thiol:disulfide interchange protein DsbG -
IHJ55_RS20980 4732193..4733098 - 906 WP_029367632.1 siderophore-interacting protein -
IHJ55_RS20985 4733355..4733606 + 252 WP_010296546.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IHJ55_RS20990 4733603..4733890 + 288 WP_010296545.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IHJ55_RS20995 4733986..4735338 - 1353 WP_010296544.1 glutathione-disulfide reductase -
IHJ55_RS21000 4735467..4736309 - 843 WP_039316638.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
IHJ55_RS21005 4736591..4736974 - 384 WP_203470580.1 TfoX/Sxy family protein -
IHJ55_RS21010 4737097..4738452 - 1356 WP_203470581.1 alkyl/aryl-sulfatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10991.08 Da        Isoelectric Point: 10.0867

>T177840 WP_010296545.1 NZ_CP063242:4733603-4733890 [Pectobacterium carotovorum]
MSYSVKFREDALKEWLKLDKAIQQQFAKKLKKCCENPHIPAAKLRGMKDCYKIKLRTSGFCLVYEVIDDVLVIAVVAVGK
RERSGVYHLASERMR

Download         Length: 288 bp

>T177840 NZ_CP083716:c122779-122033 [Bacillus velezensis]
ATGCTTTTGTTTTTTCAGATTATGGTGTGGACGATGGCGGCCGCACTCATTTTATATGTGTACGCATCCTGGCGGTATGA
GGCAAAGGTAAAAGAAAAAATGTTTGCCATCCGTAAAACGTGGTATTTACTATTTGTACTGGGCTCCATGGTCTATTGGA
CATATGATCCCGAATCGCTCTTTGCCGCATGGAGACAATATTTGATTGTTGCCGTCTGCTTTGCCCTTATTGATGCGTTT
ATCTTTTTGAGCGCGTATATCAAAAAGCTCGCCGGCAATGAATTAGAGACGGATACGCGGGAAATTTTAGAAGAAAATAA
CGAAATGCTTCACTCCTATCTTGAAAAACTGAAAACCTATCAATATCTGTTGAAAAATGAACCGATCCATGTATATTATG
GAAGTACAGAAGCTTATGCGGAAGGCATCAGCAGACTGCTGGCCGCTTATGCCGAAAAAATGAATGTCACGGCTTCCTTG
TGCGACTATTCCGCACAATCGGATAAGGACCGCTTGACGGAGCATATGCCTGATGCGGCAGACGTTCAGTCCCGTCTTAA
CCGTAAAGACGTCTACTATGATCAAAAAGGCAGGCTTGTGCTTATTCCGTTTACAGTCCAAAACCGCCATTACGTGATCA
AACTCACGTCGGAAAACCTGTTGACGGAATTCGATTATTTGCTTTTCACATCGCTAACGAGCATTTATGATTTAATGCTG
CCAATAGAAGAGGAAGGTGACGGTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9131.50 Da        Isoelectric Point: 4.0785

>AT177840 WP_010296546.1 NZ_CP063242:4733355-4733606 [Pectobacterium carotovorum]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVEVDLD
SFL

Download         Length: 252 bp

>AT177840 NZ_CP083716:c122032-121862 [Bacillus velezensis]
ATGGAGCAGGCATTTCAAAACGGGCAGCCGGAACAAAGAGCGAAACCGTTCAAAATGTTTAAAAAACGTTCAATGACAAG
TATCGCAAGTTACCAGGTCAGCCCTCATACCGCCAGAATTTTCAAAGAAAACGAGCGGCTGATTGACAAGTATAAACAAA
AAAAAGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A837DHH7

Antitoxin

Source ID Structure
AlphaFold DB A0A837DL69

References