Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 4226657..4228355 Replicon chromosome
Accession NZ_CP063242
Organism Pectobacterium carotovorum strain XP-13

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag IHJ55_RS18720 Protein ID WP_039539679.1
Coordinates 4227426..4228355 (+) Length 310 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag IHJ55_RS18715 Protein ID WP_103161895.1
Coordinates 4226657..4227439 (+) Length 261 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHJ55_RS18690 4222780..4223979 - 1200 WP_203470456.1 SIR2 family protein -
IHJ55_RS18695 4224245..4224748 - 504 WP_203470457.1 GNAT family N-acetyltransferase -
IHJ55_RS18700 4224745..4225038 - 294 WP_203470458.1 DUF1778 domain-containing protein -
IHJ55_RS18705 4225526..4225735 - 210 WP_039470597.1 helix-turn-helix domain-containing protein -
IHJ55_RS18710 4225732..4226328 - 597 WP_203470459.1 ash family protein -
IHJ55_RS18715 4226657..4227439 + 783 WP_103161895.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
IHJ55_RS18720 4227426..4228355 + 930 WP_039539679.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
IHJ55_RS18725 4228642..4229544 - 903 WP_203470460.1 LysR family transcriptional regulator -
IHJ55_RS18730 4229673..4229936 + 264 WP_010286385.1 DUF2798 domain-containing protein -
IHJ55_RS18735 4230028..4230813 - 786 WP_203470461.1 phosphonate metabolism protein PhnP -
IHJ55_RS18740 4230852..4231421 - 570 WP_203471308.1 ribose 1,5-bisphosphokinase -
IHJ55_RS18745 4231532..4231744 - 213 Protein_3665 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -
IHJ55_RS18750 4231741..4231962 - 222 Protein_3666 ATP-binding cassette domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(14-262)

Antitoxin

Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system

(95-247)


Sequences

Toxin        


Download         Length: 310 a.a.        Molecular weight: 35176.61 Da        Isoelectric Point: 5.9099

>T177837 WP_039539679.1 NZ_CP063242:4227426-4228355 [Pectobacterium carotovorum]
MDQRDIYARQVKLLMTALPYVAKEPCFALKGGTAINLFVQDFPRLSVDIDLVYQTFIDRDTDLIAIDDALMRITESLNGR
LGITAIQQENKADEKRIIVNTVDAQIKIEVSPVWRGLLLPPAEMPVCEQVEMEFGFTTMNVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPGLTRELFDGFLCYLAGHPRPIAELLAPNWDIARIATLYQQEFSGMTQHETSLESLLSVTTLLPQAL
RSHFTAQDKQFLLSYKQNTPDWSLYRYPDIQHLPAIRWKQHNLSALHAKNPAKFSTAVSKLEKVLEQRF

Download         Length: 930 bp

>T177837 NZ_CP083710:c45574-45089 [Enterobacter cloacae complex sp. ECL352]
GTGGGACGTGTAACAGCACCAGAACCATTATCCAGTTGCCATCAACTTGCTGAGTTCGCCAGTGGTGAGACTGTACTTGA
TGACTGGCTTAAACAGAGAGGATTGAAAAACCAGGCTCTGGGGGCTGCCCGAACGTTCGTAGTTTGTAAAGCAAACACGA
AACAGGTTGCCGGTTTTTACTCTCTGGCCACCGGCAGCGTTAACCACGTGGAAGCAACGGGAAGTCTCAGGCGCAACATG
CCAGATCCTATTCCGGTAATCATACTTGCTCGCCTGGCAGTCGATGTTTCATTCCGGGGAAAGGGGCTCGGGGCCGATTT
ACTGCATGATGCAGTTCTGCGCTGTTATCGTGTAGCTGAGAATATTGGAGTCCGTGCAATTATGGTTCATGCACTGACTG
AAGAAGCCAAAAGTTTTTATCTTCATCATGGCTTTAAGCCATCGCAAACCCAGGAACGTACACTGTTTCTCAAGTTACCA
CAGTAG

Antitoxin


Download         Length: 261 a.a.        Molecular weight: 29253.59 Da        Isoelectric Point: 9.1334

>AT177837 WP_103161895.1 NZ_CP063242:4226657-4227439 [Pectobacterium carotovorum]
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGYSHYTELGKPQVWLTLPAYIKLPGWFAAFEPSATFVVLYTSGLSVDVMPFTTELKIGDRRLTGSVPELAAYEIA
SGVPTQISFEHADALFQGLHLLSPRKLQALLCASHSVKTNRVMLYLAQRNGHPYFQYLDKSGIETGAGKRQIVPGGWLEP
DYQITVPREFKSKGVENGSA

Download         Length: 783 bp

>AT177837 NZ_CP083710:c45828-45562 [Enterobacter cloacae complex sp. ECL352]
ATGAAATCAGATGTTCAGCTCAACCTCAGAGCCAAAGAATCTCAAAGAGCACTTATTGATGCTGCAGCAGAGATTCTCCA
TAAATCACGCACAGACTTCATTCTGGAAATGGCATGCCAGGCGGCCGAGAATGTTATCCTCGACCGTCGCGTTTTTAATT
TTAACGATGAGCAGTACGCAGAGTTTATTGATATGCTCGATGCACCAGTTGCGGATAACGTTGCCATTGATAAACTGCTG
GCAAGGAAACCTCAGTGGGACGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References