Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4045902..4046562 Replicon chromosome
Accession NZ_CP063242
Organism Pectobacterium carotovorum strain XP-13

Toxin (Protein)


Gene name cptA Uniprot ID A0A837DIN4
Locus tag IHJ55_RS17835 Protein ID WP_039275532.1
Coordinates 4045902..4046315 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1V2R9A9
Locus tag IHJ55_RS17840 Protein ID WP_039355397.1
Coordinates 4046296..4046562 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHJ55_RS17810 4041706..4043034 + 1329 WP_010301826.1 MHS family MFS transporter -
IHJ55_RS17815 4043236..4043622 + 387 WP_203470410.1 thioesterase family protein -
IHJ55_RS17820 4043962..4044480 + 519 WP_044204035.1 flavodoxin FldB -
IHJ55_RS17825 4044509..4044832 + 324 WP_010301820.1 hypothetical protein -
IHJ55_RS17830 4044898..4045833 - 936 WP_010301818.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
IHJ55_RS17835 4045902..4046315 - 414 WP_039275532.1 protein YgfX Toxin
IHJ55_RS17840 4046296..4046562 - 267 WP_039355397.1 FAD assembly factor SdhE Antitoxin
IHJ55_RS17845 4046798..4047799 + 1002 WP_161508817.1 tRNA-modifying protein YgfZ -
IHJ55_RS17850 4048067..4048714 - 648 WP_010301806.1 hemolysin III family protein -
IHJ55_RS17855 4048993..4049601 + 609 WP_095701613.1 HD domain-containing protein -
IHJ55_RS17860 4049656..4050660 + 1005 WP_010301796.1 LacI family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16311.26 Da        Isoelectric Point: 10.7911

>T177835 WP_039275532.1 NZ_CP063242:c4046315-4045902 [Pectobacterium carotovorum]
VAQWRCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNGKDKQQLWLASDSMGDDEWRHLRQILLQQKHWAR

Download         Length: 414 bp

>T177835 NZ_CP083709:2894886-2895173 [Enterobacter cloacae complex sp. ECL352]
ATGCCAACGGAGTTTGAATGGGATACCAACAAAGCGAAAAGCAATCTCATTAAGCATGGGATCCGCTTTGAAGAAGCTGT
TCTGGTGTTTGACGATCCTTACCATTTATCTTTGCAGGATCGTCATGAAAATGGAGAGTTCCGTTGGCAGACCATTGGCC
TTGTACATGGTCTAATTGTCATTATGGTCGCACACACGGTACGTTTTGAAAGTGGTGACGAAGTCATTCGAATCATTAGC
GCACGAAAGGCGGACCGTAAAGAGAGGAGCCGTTATGAGCATGGTTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10506.99 Da        Isoelectric Point: 6.2223

>AT177835 WP_039355397.1 NZ_CP063242:c4046562-4046296 [Pectobacterium carotovorum]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPKDGELKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT177835 NZ_CP083709:2895160-2895462 [Enterobacter cloacae complex sp. ECL352]
ATGAGCATGGTTAAACATAAACGCGGTAGTGCGCCTGAGATGAGTGCTCGCCGTGAGGCTGAGCTCAAAGCACTAGCCGA
AAAATCGGAAGCAGAGATTGATTACAGCGATATCCCTGCCACGGGAGATGAACAGTGGTCAGGGGCGGTGCGAGGGAAGT
TCTATCGGCCACTCAAAACTCAGGCGTCTGTACGTATCGACGCTGACGTGATGGAGTGGCTTAAACGGCCTGGAAAAGGT
TACCAGACGAGGCTCAATGCCATTTTGCGTGAAGCTATGCTGCGCGATCAAAACAAAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A837DIN4

Antitoxin

Source ID Structure
AlphaFold DB A0A1V2R9A9

References