Detailed information of TA system TA177832

Bioinformatically predicted

Overview

TA module

• Type: VII
• Classification (family/domain): HepT-MntA/HepT(toxin)
• Location: 3277179..3277978
• Replicon: chromosome
• Accession: NZ_CP063242
• Organism: Pectobacterium carotovorum strain XP-13

Toxin (Protein)

• Gene name: hepT
• Uniprot ID: -
• Locus tag: IHJ55_RS14505
• Protein ID: WP_039540618.1
• Coordinates: 3277559..3277978 (+)
• Length: 140 a.a.

Antitoxin (Protein)

• Gene name: mntA
• Uniprot ID: -
• Locus tag: IHJ55_RS14500
• Protein ID: WP_039540621.1
• Coordinates: 3277179..3277562 (+)
• Length: 128 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IHJ55_RS14485	3272388..3273524	-	1137	WP_010296760.1	polysaccharide export protein	-
IHJ55_RS14490	3273650..3274729	-	1080	WP_039506648.1	UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase	-
IHJ55_RS14495	3275479..3277065	+	1587	WP_203470231.1	TerC family protein	-
IHJ55_RS14500	3277179..3277562	+	384	WP_039540621.1	nucleotidyltransferase domain-containing protein	Antitoxin
IHJ55_RS14505	3277559..3277978	+	420	WP_039540618.1	DUF86 domain-containing protein	Toxin
IHJ55_RS14510	3278022..3279374	-	1353	WP_203470232.1	anaerobic C4-dicarboxylate transporter DcuC	-
IHJ55_RS14515	3279639..3281474	-	1836	WP_203470233.1	outer membrane assembly protein AsmA	-
IHJ55_RS14520	3281538..3282119	-	582	WP_005974037.1	dCTP deaminase	-
IHJ55_RS14525	3282227..3282868	-	642	WP_010296746.1	uridine kinase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease HepT-like (13-130)

Antitoxin

• Polymerase beta, nucleotidyltransferase (4-93)

Sequences

Toxin

Protein

• Length: 140 a.a.
• Molecular weight: 16068.37 Da
• Isoelectric Point: 6.9682

>T177832 WP_039540618.1 NZ_CP063242:3277559-3277978 [Pectobacterium carotovorum]
MTDILLNKSSTIQRCLRRIREEFDTEEGFRQNFTKQDSVILNIQRACEASIDIANYLIRIKQLGIPQSSRDSFALLAANQ
IITIDLSDNLQKMVGLRNIAVHDYQALNLDIVIHVISHRLSDFEHFIKQIARYSDSQHL

Nucleotide

• Length: 420 bp

>T177832 NZ_CP083709:c1495761-1495351 [Enterobacter cloacae complex sp. ECL352]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCGCAGTGGATGTCTTTATTGCTCCACGGCCTGGTCGCGGC
CTTTGTTTTACTGATGCCGTGGCCGCTGAGCTATACGCCGCTGTGGCTGCTGTTACTGTCGTTTGTCGTTTTTGACAGCG
TACGCAGCCAGCGTCGCATTAATGCCCGTCAGGGAGAGATTAAATTACTGATGGATTCCCGCCTGCGCTGGCAGGGTAAA
GAGTGGGATATTCTCGGTATGCCCTGGATGCTCAACTGCGGCATGATGTTACGGTTACGCAAGGTGGACGGCGGGCGTTG
CCAGCATCTGTGGCTGGCGGCTGACAGTATGGATGCTGCCGAGTGGCGAGACCTGCGCCGGATGCTGTTGCAACAGACGA
CGCAGGGGTAA

Antitoxin

Protein

• Length: 128 a.a.
• Molecular weight: 14418.66 Da
• Isoelectric Point: 4.7463

>AT177832 WP_039540621.1 NZ_CP063242:3277179-3277562 [Pectobacterium carotovorum]
MFDKIVLTLKKQMPDIKIIYLFGSQATGNARADSDIDIAIMATRALDPIERWELSNQLAKEMGHDVDLIDLLQASTVLKM
EIVRNGKLLYDAETAAGEFEMTTLSMYQHLQKERADIIRSFNQDLKA

Nucleotide

• Length: 384 bp

>AT177832 NZ_CP083709:c1496008-1495742 [Enterobacter cloacae complex sp. ECL352]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCGTGCCGTCGCGGCATGCGTGAACTTGATATTTCCATCATGCCTTT
CTTCGAATATGAGTATGACAGCTTAAGCGATGATGATAAGCGTCTGTTTGTTCGCCTGCTTGAGTCTGACGATCCGGATT
TATTCAACTGGCTGATGAACCACGGCAAACCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA