Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 2990671..2991224 Replicon chromosome
Accession NZ_CP063242
Organism Pectobacterium carotovorum strain XP-13

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag IHJ55_RS13440 Protein ID WP_203470164.1
Coordinates 2990671..2990985 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag IHJ55_RS13445 Protein ID WP_203470165.1
Coordinates 2990988..2991224 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHJ55_RS13415 2986274..2986607 - 334 Protein_2624 transposase -
IHJ55_RS13420 2986734..2987702 - 969 WP_203470162.1 Gfo/Idh/MocA family oxidoreductase -
IHJ55_RS13425 2987757..2988350 - 594 WP_203470163.1 NAD(P)H-dependent oxidoreductase -
IHJ55_RS13430 2988569..2989471 + 903 WP_039536805.1 AraC family transcriptional regulator -
IHJ55_RS13435 2990184..2990471 + 288 WP_010305018.1 hypothetical protein -
IHJ55_RS13440 2990671..2990985 - 315 WP_203470164.1 CcdB family protein Toxin
IHJ55_RS13445 2990988..2991224 - 237 WP_203470165.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
IHJ55_RS13450 2991374..2991820 - 447 Protein_2631 ArdC family protein -
IHJ55_RS13455 2992183..2993076 + 894 Protein_2632 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2992183..2992350 167


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11535.48 Da        Isoelectric Point: 7.9859

>T177831 WP_203470164.1 NZ_CP063242:c2990985-2990671 [Pectobacterium carotovorum]
MQFTVYGNTGKSVVYPLLLDVTSDIIGQLNRRIVIPLLPIEKYPAGRRPDRLVPVVRLTDGKEYAVMTHELASIPVQALG
AVFCDASQYRTQVKAALDFLIDGF

Download         Length: 315 bp

>T177831 NZ_CP083709:1263589-1263888 [Enterobacter cloacae complex sp. ECL352]
ATGATTAGTTATTTTCGGGATCAATGGCTTGAGGATTTTTTTCTTTACGGCAGATCGAGCAATGTTATTCCTGCAAATCT
GGAAACAGCGCTTGCGAGAAAGCTCGATATCATCAGGGCAGCAACCTCGCACAGGGATTTGCGATCGCCACCGGGCAATA
TGTATGAAGCATTGAATCCTCCGCTAAAGGGATATTCCTCAATCCGGGTAAACAGGCAATACAGGCTCGTATTTCGCTGG
ACAGAGGGTAAAGCAGAAGATCTCTACCTCTCTCCACACAAGTACACGCAACACAAGTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8861.93 Da        Isoelectric Point: 8.0494

>AT177831 WP_203470165.1 NZ_CP063242:c2991224-2990988 [Pectobacterium carotovorum]
MTAKPRNTQSVTITVERALLVRARGAGINLSATLSTALDAELRRHEAKKWQEENREALAALNRFHDEQGCFSDEYRTF

Download         Length: 237 bp

>AT177831 NZ_CP083709:1263899-1264246 [Enterobacter cloacae complex sp. ECL352]
ATGACACTTCAACAGGCACTCCGCAAACCCACCACGCCGGGCGACGTGATGCAGTATGAGTATCTTGAACCGCTCAATCT
GAAAATCAGCGATCTGGCGGAGATGCTCAATGTTCACCGCAACACCATCAGCGCGCTGGTCAATAACAATCGCAAGCTGA
CTGCCGATATGGCGATCAAACTGGCAAAAGCCTTTGATACCACGATTGAATTTTGGCTTAACTTACAGCTGAACGTCGAT
ATCTGGGAAGCGCAATCCAACCCCAGGACGCAGGAGGAGCTAAGCCGTATAAAGACCGTTGCGGACGTCATGGCTAAGCG
AAAATCTGGCCAGCCGGATGTAGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References