Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1118508..1119033 Replicon chromosome
Accession NZ_CP063242
Organism Pectobacterium carotovorum strain XP-13

Toxin (Protein)


Gene name relE Uniprot ID A0A1D7Z1B4
Locus tag IHJ55_RS04980 Protein ID WP_005973612.1
Coordinates 1118749..1119033 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID C6D956
Locus tag IHJ55_RS04975 Protein ID WP_005973616.1
Coordinates 1118508..1118759 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHJ55_RS04955 1113632..1114648 - 1017 WP_203470875.1 NAD(P)-dependent alcohol dehydrogenase -
IHJ55_RS04960 1114738..1115661 + 924 WP_203470876.1 LysR family transcriptional regulator -
IHJ55_RS04965 1115800..1116566 - 767 Protein_967 conjugal transfer protein TraF -
IHJ55_RS04970 1116617..1117833 + 1217 Protein_968 IS3 family transposase -
IHJ55_RS04975 1118508..1118759 + 252 WP_005973616.1 prevent-host-death protein Antitoxin
IHJ55_RS04980 1118749..1119033 + 285 WP_005973612.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IHJ55_RS04985 1119443..1119633 + 191 Protein_971 recombinase -
IHJ55_RS04990 1120967..1121614 - 648 WP_010308382.1 EcsC family protein -
IHJ55_RS04995 1122037..1122522 + 486 WP_161502189.1 Hcp family type VI secretion system effector -
IHJ55_RS05000 1122966..1123598 - 633 WP_203470877.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11010.96 Da        Isoelectric Point: 10.1716

>T177830 WP_005973612.1 NZ_CP063242:1118749-1119033 [Pectobacterium carotovorum]
MSYKLEFEEHALKEFKKLGAPVREQFTKKLKEVLQNPHVPANRLHGMADCYKIKLRSAGYRLVYQVLEHEIVVLVLAVGK
RERSEVYKTAKDRL

Download         Length: 285 bp

>T177830 NZ_CP083709:c639846-639493 [Enterobacter cloacae complex sp. ECL352]
GTGTGGGCAATTAACACGACGGACAGGTTTGATCGCTGGTTCACATCGCTTGACGATACCGATCGCGCCAGCGTACTTGC
AGCACTGCTTGTTTTGCGAGAGAAGGGGCCGGGTTTATCGAGACCCTACGCTGATACGCTTAAAGGCTCCCGTCACAGCA
ACATGAAAGAGCTACGTATTCAGAGTAAGGGCGATCCATTACGGGCGTTTTTCGCCTTTGACCCAAACCGTACTGGCATC
ATACTTTGTGCGGGCAATAAGGTCGGCAATGAAAGGCGATTCTACGATGAGATGCTTCTCGTTGCTGACCGGGAATTCAC
TCACTGGCTGAATATATTAAAAGAGAGGGAATAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9079.35 Da        Isoelectric Point: 5.0807

>AT177830 WP_005973616.1 NZ_CP063242:1118508-1118759 [Pectobacterium carotovorum]
MSVQPILANAAVSISDFKKSPNAALKEANGEPVAVLTNGRISGYYVSPETWEALADYQEDIELAKIARSRMKGKRVKVDL
DEL

Download         Length: 252 bp

>AT177830 NZ_CP083709:c639488-639186 [Enterobacter cloacae complex sp. ECL352]
ATGGGAAGAACCCTTGAGCAGCTTATAGCGGATGAAAAGCCGGAGGTTGTCGCCAGCGCTCAGGCGCTAGCAACGGATAT
TTTGCTCAACATTCATCTTGCTGAGTTACGCGAGAAAGTACAAAAAACGCAGGTAGAAATGGCGCAGGCGTTGGGTATCA
GGCAACCTACCGTTGCGGTAATGGAAAAGCCCGGGCGCGATTTGAAACTCTCTTCTCTCAAGCGCTACGTTGAGGCTGCG
GGCGGAAAGCTGCGGCTTGATGTGGAGCTGCCGGATGGCTCGCACTATGAGTTTGTGCTGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7Z1B4

Antitoxin

Source ID Structure
AlphaFold DB A0A0G4JQP6

References