Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-YafN |
Location | 4563542..4564077 | Replicon | chromosome |
Accession | NZ_CP063241 | ||
Organism | Pectobacterium brasiliense strain ZLMLSHJ5 |
Toxin (Protein)
Gene name | relE | Uniprot ID | C6DJA0 |
Locus tag | IHJ54_RS20245 | Protein ID | WP_015842269.1 |
Coordinates | 4563790..4564077 (+) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | Q6DB37 |
Locus tag | IHJ54_RS20240 | Protein ID | WP_010281712.1 |
Coordinates | 4563542..4563793 (+) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IHJ54_RS20210 | 4558981..4559307 | + | 327 | WP_014913674.1 | helix-turn-helix domain-containing protein | - |
IHJ54_RS20215 | 4559292..4559606 | + | 315 | WP_039528006.1 | HipA N-terminal domain-containing protein | - |
IHJ54_RS20220 | 4559603..4560643 | + | 1041 | WP_203449716.1 | HipA domain-containing protein | - |
IHJ54_RS20225 | 4560703..4561326 | - | 624 | WP_203449717.1 | LysE family translocator | - |
IHJ54_RS20230 | 4561594..4562349 | + | 756 | WP_203449718.1 | thiol:disulfide interchange protein DsbG | - |
IHJ54_RS20235 | 4562383..4563288 | - | 906 | WP_203449719.1 | siderophore-interacting protein | - |
IHJ54_RS20240 | 4563542..4563793 | + | 252 | WP_010281712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
IHJ54_RS20245 | 4563790..4564077 | + | 288 | WP_015842269.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
IHJ54_RS20250 | 4564197..4565549 | - | 1353 | WP_014913667.1 | glutathione-disulfide reductase | - |
IHJ54_RS20255 | 4565677..4566519 | - | 843 | WP_039527996.1 | 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ | - |
IHJ54_RS20260 | 4566738..4567466 | + | 729 | WP_039498362.1 | DUF1266 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11074.15 Da Isoelectric Point: 10.3527
>T177826 WP_015842269.1 NZ_CP063241:4563790-4564077 [Pectobacterium brasiliense]
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGMKDCYKIKLRASGFRLVYEVIDDVLIIAVVAVGK
RERSGVYHLASERMR
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGMKDCYKIKLRASGFRLVYEVIDDVLIIAVVAVGK
RERSGVYHLASERMR
Download Length: 288 bp
>T177826 NZ_CP083704:37001-37153 [Escherichia coli]
ATGCCACAGCGAACGTTTTTAATGATGTTAATCGTCGTCTGTGTGACGATTCTGTGTTTTGTCTGGATGGTGAGGGATTC
GCTTTGCGGACTCCGGCTCCAGCAGGGAAACACAGTGCTTGTGGCAACGTTAGCCTACGAAGTTAAACGTTAA
ATGCCACAGCGAACGTTTTTAATGATGTTAATCGTCGTCTGTGTGACGATTCTGTGTTTTGTCTGGATGGTGAGGGATTC
GCTTTGCGGACTCCGGCTCCAGCAGGGAAACACAGTGCTTGTGGCAACGTTAGCCTACGAAGTTAAACGTTAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9117.47 Da Isoelectric Point: 4.0637
>AT177826 WP_010281712.1 NZ_CP063241:4563542-4563793 [Pectobacterium brasiliense]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL
Download Length: 252 bp
>AT177826 NZ_CP083704:c36949-36889 [Escherichia coli]
GAGGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
GAGGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3S0XQ75 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0M2EZP0 |