Detailed information of TA system TA177823

Bioinformatically predicted

Overview

TA module

• Type: VII
• Classification (family/domain): HepT-MntA/HepT(toxin)
• Location: 1507158..1507957
• Replicon: chromosome
• Accession: NZ_CP063241
• Organism: Pectobacterium brasiliense strain ZLMLSHJ5

Toxin (Protein)

• Gene name: hepT
• Uniprot ID: -
• Locus tag: IHJ54_RS06555
• Protein ID: WP_203450202.1
• Coordinates: 1507158..1507577 (-)
• Length: 140 a.a.

Antitoxin (Protein)

• Gene name: mntA
• Uniprot ID: -
• Locus tag: IHJ54_RS06560
• Protein ID: WP_039521139.1
• Coordinates: 1507574..1507957 (-)
• Length: 128 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IHJ54_RS06535	1502263..1502904	+	642	WP_010281304.1	uridine kinase	-
IHJ54_RS06540	1503012..1503593	+	582	WP_014914714.1	dCTP deaminase	-
IHJ54_RS06545	1503655..1505490	+	1836	WP_203450201.1	outer membrane assembly protein AsmA	-
IHJ54_RS06550	1505754..1507106	+	1353	WP_039287778.1	anaerobic C4-dicarboxylate transporter DcuC	-
IHJ54_RS06555	1507158..1507577	-	420	WP_203450202.1	DUF86 domain-containing protein	Toxin
IHJ54_RS06560	1507574..1507957	-	384	WP_039521139.1	nucleotidyltransferase domain-containing protein	Antitoxin
IHJ54_RS06565	1508093..1509679	-	1587	WP_014914717.1	TerC family protein	-
IHJ54_RS06570	1510430..1511509	+	1080	WP_039468166.1	UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase	-
IHJ54_RS06575	1511635..1512771	+	1137	WP_039468169.1	polysaccharide export protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease HepT-like (13-130)

Antitoxin

• Polymerase beta, nucleotidyltransferase (5-93)

Sequences

Toxin

Protein

• Length: 140 a.a.
• Molecular weight: 16096.42 Da
• Isoelectric Point: 6.9684

>T177823 WP_203450202.1 NZ_CP063241:c1507577-1507158 [Pectobacterium brasiliense]
MTDILLNKSSTIQRCLRRIREEFDTEEGFRQNFTKQDSVILNIQRACEAAIDIANYLIRIKQLGIPQSSRDSFALLAANQ
IITLELSDNLQKMVGLRNIAVHDYQTLNLDIVIHVISHRLSDFEHFIKQIARYSDSQHL

Nucleotide

• Length: 420 bp

>T177823 NZ_CP083702:41875-42273 [Escherichia coli]
ATGCTGAAGTTTATGCTCGATACCAACATCTGCATTTTTACGATAAAGAACAAACCCGCCAGCGTCAGGGAGCGTTTTAA
CCTTAACCAGGGGAGAATGTGTATCAGTTCGGTCACCCTGATGGAGCTGATATATGGTGCAGAAAAAAGCCAGATGCCTG
AACGTAATCTCGCTGTGATCGAGGGATTTGTTTCCCGCATTGATGTTCTGGATTACGACGCCGCTGCAGCCATACACACC
GGCCAGATAAGAGCAGAACTTGCCCGTCAGGGACGCCCTGTCGGGCCATTTGATCAAATGATCGCAGGTCATGCCCGCTG
TCGGGGGCTGATTATTGTGACTAATAACACCCGGGAATTTGAACGTGTGGGCGGCCTGAGAATTGAAGACTGGAGCTGA

Antitoxin

Protein

• Length: 128 a.a.
• Molecular weight: 14326.50 Da
• Isoelectric Point: 4.7434

>AT177823 WP_039521139.1 NZ_CP063241:c1507957-1507574 [Pectobacterium brasiliense]
MFDEIVLTLKKQMPDIKIIYLFGSQATGNARADSDVDIAIMATKALDPVERWELSHQLAKTVGHDVDLIDLLQASTVLKM
EIVRNGKLLYDAEATAGEFEMTTLSMYQHLQKERADIIRSFNQDLKA

Nucleotide

• Length: 384 bp

>AT177823 NZ_CP083702:41648-41875 [Escherichia coli]
ATGGAAACCACCGTATTTCTCAGCAACCGCAGCCAGGCGGTCAGACTGCCAAAAGCGGTTGCATTGCCGGAAAACGTAAA
ACGCGTTGAAGTGATTGCTATCGGACGAACCCGACTCATTACGCCAGCCGGAGAGACATGGGACGAATGGTTCGACGGAC
ACAGCGTCAGCGCCGATTTTATGGATAACAGGGAACAGCCCGGCATGCAGGAACGGGAGTCATTCTGA