Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1021487..1022001 Replicon chromosome
Accession NZ_CP063241
Organism Pectobacterium brasiliense strain ZLMLSHJ5

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag IHJ54_RS04420 Protein ID WP_203450517.1
Coordinates 1021487..1021762 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag IHJ54_RS04425 Protein ID WP_203450087.1
Coordinates 1021783..1022001 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHJ54_RS04400 1016962..1017177 + 216 WP_203450083.1 DUF3577 domain-containing protein -
IHJ54_RS04405 1017280..1018551 + 1272 WP_203450084.1 hypothetical protein -
IHJ54_RS04410 1018555..1019091 + 537 WP_203450085.1 hypothetical protein -
IHJ54_RS04415 1019079..1021019 + 1941 WP_203450086.1 hypothetical protein -
IHJ54_RS04420 1021487..1021762 - 276 WP_203450517.1 CcdB family protein Toxin
IHJ54_RS04425 1021783..1022001 - 219 WP_203450087.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
IHJ54_RS04430 1022016..1022264 - 249 WP_010299606.1 helix-turn-helix domain-containing protein -
IHJ54_RS04435 1022350..1022604 - 255 WP_203450088.1 helix-turn-helix domain-containing protein -
IHJ54_RS04440 1022708..1022950 + 243 WP_072036092.1 helix-turn-helix domain-containing protein -
IHJ54_RS04450 1023778..1025931 + 2154 WP_203450089.1 ornithine decarboxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(9-90)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10448.10 Da        Isoelectric Point: 4.6533

>T177821 WP_203450517.1 NZ_CP063241:c1021762-1021487 [Pectobacterium brasiliense]
IQTNQQVKKQSDIVDTPKRRMVIPLIEAHHLSEKVNKKLFPLIRIDDGEDYRLMTTEISSVPVEVIGEVIADLGEYADEI
KDVINLMFWGI

Download         Length: 276 bp

>T177821 NZ_CP083701:4762785-4763120 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGATTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8181.26 Da        Isoelectric Point: 10.2013

>AT177821 WP_203450087.1 NZ_CP063241:c1022001-1021783 [Pectobacterium brasiliense]
MKRRISIAVDKGDYQILSAAGVNISELVNDALGKEARRIKTEAWKKENREGMENVARFIAKNGSFADENRNW

Download         Length: 219 bp

>AT177821 NZ_CP083701:4762537-4762785 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References