177820

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 758770..759430 Replicon chromosome
Accession NZ_CP063241
Organism Pectobacterium brasiliense strain ZLMLSHJ5

Toxin (Protein)


Gene name cptA Uniprot ID A0A837DIN4
Locus tag IHJ54_RS03320 Protein ID WP_039275532.1
Coordinates 759017..759430 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1D7Z1Z6
Locus tag IHJ54_RS03315 Protein ID WP_005971623.1
Coordinates 758770..759036 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHJ54_RS03295 754733..755737 - 1005 WP_203449988.1 LacI family DNA-binding transcriptional regulator -
IHJ54_RS03300 755792..756400 - 609 WP_014914174.1 HD domain-containing protein -
IHJ54_RS03305 756831..757478 + 648 WP_010279833.1 hemolysin III family protein -
IHJ54_RS03310 757533..758534 - 1002 WP_014914175.1 tRNA-modifying protein YgfZ -
IHJ54_RS03315 758770..759036 + 267 WP_005971623.1 FAD assembly factor SdhE Antitoxin
IHJ54_RS03320 759017..759430 + 414 WP_039275532.1 protein YgfX Toxin
IHJ54_RS03325 759499..760434 + 936 WP_203449989.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
IHJ54_RS03330 760500..760823 - 324 WP_203449990.1 hypothetical protein -
IHJ54_RS03335 760852..761370 - 519 WP_014914178.1 flavodoxin FldB -
IHJ54_RS03340 761714..762100 - 387 WP_039282122.1 thioesterase family protein -
IHJ54_RS03345 762305..763633 - 1329 WP_039282120.1 MHS family MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16311.26 Da        Isoelectric Point: 10.7911

>T177820 WP_039275532.1 NZ_CP063241:759017-759430 [Pectobacterium brasiliense]
VAQWRCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNGKDKQQLWLASDSMGDDEWRHLRQILLQQKHWAR

Download         Length: 414 bp

>T177820 NZ_CP083701:4625405-4625812 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10507.94 Da        Isoelectric Point: 5.1392

>AT177820 WP_005971623.1 NZ_CP063241:758770-759036 [Pectobacterium brasiliense]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT177820 NZ_CP083701:4625158-4625424 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A837DIN4

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z1Z6

References