Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | stbDE/ParE-DnaT |
Location | 347530..348061 | Replicon | chromosome |
Accession | NZ_CP063241 | ||
Organism | Pectobacterium brasiliense strain ZLMLSHJ5 |
Toxin (Protein)
Gene name | stbE | Uniprot ID | A0A086EVU3 |
Locus tag | IHJ54_RS01550 | Protein ID | WP_039282785.1 |
Coordinates | 347774..348061 (+) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | stbD | Uniprot ID | A0A1V2R9J2 |
Locus tag | IHJ54_RS01545 | Protein ID | WP_039282788.1 |
Coordinates | 347530..347784 (+) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IHJ54_RS01525 | 342531..344549 | - | 2019 | WP_203449846.1 | penicillin-binding protein activator | - |
IHJ54_RS01530 | 344611..345498 | + | 888 | WP_040038101.1 | 16S rRNA (cytidine(1402)-2'-O)-methyltransferase | - |
IHJ54_RS01540 | 346014..347330 | + | 1317 | WP_080163527.1 | IS4 family transposase | - |
IHJ54_RS01545 | 347530..347784 | + | 255 | WP_039282788.1 | plasmid stabilization protein | Antitoxin |
IHJ54_RS01550 | 347774..348061 | + | 288 | WP_039282785.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
IHJ54_RS01555 | 348240..349025 | + | 786 | WP_010280213.1 | 4,5-DOPA dioxygenase extradiol | - |
IHJ54_RS01560 | 349093..350253 | - | 1161 | WP_203449847.1 | glutathionylspermidine synthase family protein | - |
IHJ54_RS01565 | 350265..350939 | - | 675 | WP_010280216.1 | DUF1190 family protein | - |
IHJ54_RS01570 | 351209..352600 | - | 1392 | WP_039522250.1 | outer membrane channel protein TolC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | flank | IS/Tn | - | - | 346014..347330 | 1316 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11011.96 Da Isoelectric Point: 10.7694
>T177817 WP_039282785.1 NZ_CP063241:347774-348061 [Pectobacterium brasiliense]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQIYSDTKGRSA
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQIYSDTKGRSA
Download Length: 288 bp
>T177817 NZ_CP083701:4351920-4352234 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9208.38 Da Isoelectric Point: 3.7947
>AT177817 WP_039282788.1 NZ_CP063241:347530-347784 [Pectobacterium brasiliense]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL
Download Length: 255 bp
>AT177817 NZ_CP083701:4352231-4352647 [Escherichia coli]
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A086EVU3 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1V2R9J2 |