Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/- |
Location | 151074..151708 | Replicon | chromosome |
Accession | NZ_CP063241 | ||
Organism | Pectobacterium brasiliense strain ZLMLSHJ5 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | - |
Locus tag | IHJ54_RS00640 | Protein ID | WP_080162911.1 |
Coordinates | 151074..151349 (+) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | A0A433N1R7 |
Locus tag | IHJ54_RS00645 | Protein ID | WP_014917022.1 |
Coordinates | 151346..151708 (+) | Length | 121 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IHJ54_RS00625 | 148094..149464 | - | 1371 | WP_010281575.1 | envelope stress sensor histidine kinase CpxA | - |
IHJ54_RS00630 | 149461..150159 | - | 699 | WP_010281574.1 | envelope stress response regulator transcription factor CpxR | - |
IHJ54_RS00635 | 150313..150837 | + | 525 | WP_203449802.1 | cell-envelope stress modulator CpxP | - |
IHJ54_RS00640 | 151074..151349 | + | 276 | WP_080162911.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
IHJ54_RS00645 | 151346..151708 | + | 363 | WP_014917022.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
IHJ54_RS00650 | 152082..153269 | + | 1188 | WP_039511454.1 | sugar transporter | - |
IHJ54_RS00655 | 153342..154244 | + | 903 | WP_180789217.1 | CDF family cation-efflux transporter FieF | - |
IHJ54_RS00660 | 154451..155413 | + | 963 | WP_010306854.1 | 6-phosphofructokinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10024.61 Da Isoelectric Point: 11.1875
>T177815 WP_080162911.1 NZ_CP063241:151074-151349 [Pectobacterium brasiliense]
MQGKIASLRKKQRETLSQIFKTPVLSGVKWSNIESLVTALGGEIKEGSGSRVRFLLNGSIARFHRPHPSPDTDKGALVSL
REWLESIGVKP
MQGKIASLRKKQRETLSQIFKTPVLSGVKWSNIESLVTALGGEIKEGSGSRVRFLLNGSIARFHRPHPSPDTDKGALVSL
REWLESIGVKP
Download Length: 276 bp
>T177815 NZ_CP083701:3842816-3842923 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA
Antitoxin
Download Length: 121 a.a. Molecular weight: 13504.31 Da Isoelectric Point: 4.4969
>AT177815 WP_014917022.1 NZ_CP063241:151346-151708 [Pectobacterium brasiliense]
MTKALNTPNTMVVSGQPAIISYVPEMGMFRGKFIGLSGYCDFVADSINGLRSEGEISLREYLEDCQENGIEPYEREEKVK
TFTLRYPESFGERLTIAAAERQISVNTFIVETLSEHLKQA
MTKALNTPNTMVVSGQPAIISYVPEMGMFRGKFIGLSGYCDFVADSINGLRSEGEISLREYLEDCQENGIEPYEREEKVK
TFTLRYPESFGERLTIAAAERQISVNTFIVETLSEHLKQA
Download Length: 363 bp
>AT177815 NZ_CP083701:c3842767-3842704 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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