Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 180383..180855 Replicon chromosome
Accession NZ_CP063238
Organism Serratia marcescens strain SCH909

Toxin (Protein)


Gene name relE Uniprot ID A0A2V4FUJ7
Locus tag SCH909_RS00825 Protein ID WP_060423398.1
Coordinates 180580..180855 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag SCH909_RS00820 Protein ID WP_033649649.1
Coordinates 180383..180580 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SCH909_RS00790 175576..176844 + 1269 WP_060423407.1 glycerol-3-phosphate dehydrogenase subunit GlpB -
SCH909_RS00795 176841..178040 + 1200 WP_060423404.1 anaerobic glycerol-3-phosphate dehydrogenase subunit C -
SCH909_RS00800 178076..178639 - 564 WP_033636670.1 DcrB family lipoprotein -
SCH909_RS00805 178720..179154 - 435 WP_060423401.1 GNAT family N-acetyltransferase -
SCH909_RS00810 179196..179855 - 660 WP_033636672.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
SCH909_RS00815 180076..180321 + 246 WP_025304890.1 sulfurtransferase TusA -
SCH909_RS00820 180383..180580 + 198 WP_033649649.1 hypothetical protein Antitoxin
SCH909_RS00825 180580..180855 + 276 WP_060423398.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
SCH909_RS00830 180915..183224 - 2310 WP_060423395.1 zinc/cadmium/mercury/lead-transporting ATPase -
SCH909_RS00835 183906..185369 + 1464 WP_033636674.1 serralysin family metalloprotease -
SCH909_RS00840 185425..185802 + 378 WP_060423392.1 AprI/Inh family metalloprotease inhibitor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10708.65 Da        Isoelectric Point: 11.2806

>T177797 WP_060423398.1 NZ_CP063238:180580-180855 [Serratia marcescens]
MLNIEWTRAARQDLVEIVGFIANDNPLAARKMKVLIMEAVIPAARHPRIFRRGRVDGTHEIPLHPHYLLVYQVLETHIRV
LRVLHTRRQYP

Download         Length: 276 bp

>T177797 NZ_CP083692:c791954-791565 [Leucobacter sp. Psy1]
GTGATCAGCTACCTCGACACTTCGGCGGCCTTCAAGCTCATCGCCGAAGAAACCGGTTCACCCGGACTCGCTGATTACGT
CGACGCCGCACTCGAACAGGGCACGACCTTCGTGTCCTCTTGGCTCCTGCACACAGAGTTGCACTGCGCCGCTGATCGAC
GCAACGCGATCGCCCCGGAGTCCGTCACCGCGATTCTCGATTTCGTGGAACTCATCGACGTCGAGCGCATCGACATGCAG
CGCGCAGCGACATCGGCGTGGGGCTTGAGAAGCGCGGACGCCGTTCACCTAGCCACTGCGCTCCGGGTGGAGGCCACAAC
GCTCGTCACGTACGACACTGAAATGCAGTACGCGAGTGCCCGCGTCGGCCTCCGCGTCGCGGAACCCTGA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7398.49 Da        Isoelectric Point: 4.4143

>AT177797 WP_033649649.1 NZ_CP063238:180383-180580 [Serratia marcescens]
MSILLLPTVAKMENEERTQGYERWFLERVQEAMDEPRPGIPHDDVMAEMDAVIAAAEARIKAKQA

Download         Length: 198 bp

>AT177797 NZ_CP083692:c792223-791951 [Leucobacter sp. Psy1]
ATGCAGACGATCGCCCACCGGGAGCTCCGGAACCACAGCAGTGACATCCTCGCGCGCGCCCAGGGCGGCGAAAGCTTCAC
GATCACGAATCACGGCAAGCCGGTCGCGCTGCTCACGCCACCACAACCGCAGACCACCGAGCTGGAGCGCCTCCGGGCAG
CCGGAAGGACCCTGCCCGCCCGCCGTGCACCTGGGCAGAGGATCGCCGACGTGATCCGCACCCCTGGCCTGCGGAGCCAG
GAGCTACTCGAGGACATTCGAGGAAACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2V4FUJ7

Antitoxin

Source ID Structure

References