Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1881060..1881205 Replicon chromosome
Accession NZ_CP063215
Organism Klebsiella pneumoniae strain HKU57

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1881096..1881198 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1881060..1881205 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IM695_RS09090 1876190..1878250 + 2061 WP_004151449.1 oligopeptidase B -
IM695_RS09095 1878254..1878913 - 660 WP_020324964.1 exodeoxyribonuclease X -
IM695_RS09100 1878992..1879222 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IM695_RS09105 1879335..1879709 + 375 WP_004151448.1 CopC domain-containing protein YobA -
IM695_RS09110 1879713..1880582 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
IM695_RS09115 1880599..1880937 + 339 WP_002911404.1 YebY family protein -
- 1881060..1881205 - 146 - - Antitoxin
- 1881096..1881198 + 103 - - Toxin
IM695_RS09120 1881574..1881717 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
IM695_RS09125 1881822..1882790 - 969 WP_004151446.1 VirK/YbjX family protein -
IM695_RS09130 1882947..1883600 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
IM695_RS09135 1883597..1883788 - 192 WP_002911395.1 YebW family protein -
IM695_RS09140 1883886..1884125 - 240 WP_002911393.1 YebV family protein -
IM695_RS09145 1884241..1885674 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T177733 NZ_CP063215:1881096-1881198 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT177733 NZ_CP063215:c1881205-1881060 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References