Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 418782..419266 Replicon chromosome
Accession NZ_CP063212
Organism Trueperella sp. 19M2397 strain 19OD0592

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag INS90_RS01855 Protein ID WP_197554091.1
Coordinates 418782..419045 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag INS90_RS01860 Protein ID WP_197554094.1
Coordinates 419042..419266 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
INS90_RS01830 413859..415175 - 1317 WP_197554079.1 hypothetical protein -
INS90_RS01835 415245..415451 - 207 WP_197554082.1 DUF4411 family protein -
INS90_RS01840 415451..416605 - 1155 Protein_359 ImmA/IrrE family metallo-endopeptidase -
INS90_RS01845 416891..418321 + 1431 WP_197554085.1 NAD(P)/FAD-dependent oxidoreductase -
INS90_RS01850 418448..418765 + 318 WP_197554088.1 hypothetical protein -
INS90_RS01855 418782..419045 - 264 WP_197554091.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
INS90_RS01860 419042..419266 - 225 WP_197554094.1 ribbon-helix-helix protein, CopG family Antitoxin
INS90_RS01865 419519..420451 - 933 WP_197554097.1 restriction endonuclease -
INS90_RS01870 421588..422799 - 1212 WP_197554100.1 hypothetical protein -
INS90_RS01875 423038..424225 - 1188 Protein_366 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 398403..432807 34404


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(10-87)

Antitoxin

Protein of unknown function DUF6290

(1-72)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10247.87 Da        Isoelectric Point: 10.4528

>T177696 WP_197554091.1 NZ_CP063212:c419045-418782 [Trueperella sp. 19M2397]
MTYEIHTTHHFDKAFKKLDPQTQRIIKVWITKNLVGCHDPRTLGKGLTSNRSGQWRYRVGDYRILADIQDSRLILLLIDV
GHRSKIY

Download         Length: 264 bp

>T177696 NZ_CP083631:2583308-2583526 [Klebsiella quasipneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAACAAATATGAACTTTCTGATAATGAGCTGGCGGTATTTTACTCAGCCGCCGATCATCGTCTGGCTGAAC
TGACTATGAATAAGCTGTACGATAAAATCCCGACGTCCGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8684.88 Da        Isoelectric Point: 4.8356

>AT177696 WP_197554094.1 NZ_CP063212:c419266-419042 [Trueperella sp. 19M2397]
MPTISLRVPEDELAVFKSFAKHTNTSVSEMIRQTVIERIENEYDLRVFAEYEDQKKSGKLKTRPINELWDELGL

Download         Length: 225 bp

>AT177696 NZ_CP083631:2582907-2583281 [Klebsiella quasipneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATCGCACAACTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACATCGGCTGTCAATCTCCAGTTAAATGAACTGATCGAGC
ACATTGCCACATTCGCCCTTAATTATAAAATTAAGTACGCTGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACATTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAATCGGTT
ATTTCGTTGTTTTGTCAACGCCAGCCGGGAAAATCCGGCCAGTCTTTCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References